Emerging bioinformatics for the metabolome.

Brief Bioinform

Virginia Bioinformatics Institute, and State University, Blacksburg 24061, USA.

Published: June 2002

Metabolic profiling applied to functional genomics (metabolomics) is in an early stage of development. Here, the technologies used for metabolite profiling are briefly covered, illustrated by a few pioneering studies. Issues related to bioinformatics, namely data analysis, visualisation and archival, are the main focus of this review. Arguably there is already a need for databases containing metabolite profiles specific for a single organism, and a generic repository containing all metabolite profiling results, regardless of species. Data analyses and visualisations that combine the biological context with chemistry details are suggested as being the most promising.

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http://dx.doi.org/10.1093/bib/3.2.134DOI Listing

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