Spatial analyses of disease rates are increasing as the hardware and software used in disease surveillance and cluster investigations become more accessible and easier to use. The results of these analyses should be interpreted with caution since inconsistencies in health outcome reporting and population estimates may lead to erroneous conclusions. In this report we provide an example, using data on congenital malformations in New York State, to show how under-reporting of malformations by some New York City hospitals can lead to apparent clusters of malformations in other areas of the state where reporting is more complete. We illustrate how spatial analysis techniques can be used to locate under-reporting problems and determine the extent to which the problem exists.
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http://dx.doi.org/10.1016/s1353-8292(01)00037-5 | DOI Listing |
Children (Basel)
December 2024
Department of Speech Therapy, School of Health Sciences, University of Ioannina, 45500 Ioannina, Greece.
A specific deletion on the short arm of chromosome 5 (5p) is the hallmark of the rare genetic syndrome called Cri du Chat Syndrome (CdCS). It causes severe difficulty with swallowing, speech, motor skills, and cognitive deficiencies. These arise from characteristic laryngeal abnormalities and oral-motor dysfunctions.
View Article and Find Full Text PDFGenes (Basel)
December 2024
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
The joint College of American Pathologists/American College of Medical Genetics and Genomics Cytogenetics Committee works to ensure the competency and proficiency of clinical cytogenetic testing laboratories through proficiency testing (PT) programs for various clinical tests offered by such laboratories, including the evaluation of cytogenetic abnormalities in solid tumors. Review and analyze 25 years (1999-2023) of solid tumor chromosome analysis PT results, utilizing G-banded karyograms. A retrospective review of results from 1999 to 2023 was performed, identifying the challenges addressing solid tumors.
View Article and Find Full Text PDFSkeletal Radiol
January 2025
Department of Radiology, NYU Langone Orthopedic Hospital, 301 East 17Th Street, 6Th Floor, Radiology , New York, NY, 10003, USA.
Objective: To evaluate the Neuropathy Score-Reporting and Data System (NS-RADS) MRI grading system in conjunction with electrodiagnostic (EDx) testing for radial neuropathy at the elbow.
Materials And Methods: Patients presenting between 2010 and 2023 with suspected radial neuropathy who underwent both EDx testing in the form of electromyography and nerve conduction studies and MRI within a 12-month period were evaluated. Three blinded radiologists used the NS-RADS grading system to evaluate nerve entrapment (E grades), muscle denervation (M grades) proximally within the supinator/extensor carpi radialis brevis (ECRB), and more distally within the forearm extensor muscles.
Allergy
January 2025
Department of Dermatology, Icahn School of Medicine at the Mount Sinai, New York, New York, USA.
Introduction: Chronic hand eczema (CHE) is a highly prevalent inflammatory skin condition which is often resistant to conventional treatments. Molecular insights of CHE remain limited. Tape stripping combined with high-throughput RNA sequencing can now provide a better insight into CHE pathogenesis in a minimally invasive fashion.
View Article and Find Full Text PDFAnn Otol Rhinol Laryngol
January 2025
Department of Otolaryngology-Head and Neck Surgery, Pediatric Otolaryngology, Weill Cornell Medicine, New York, NY, USA.
Objective: To evaluate the effectiveness of coordinated endoscopy with otolaryngology, pulmonology, and gastroenterology in diagnosing and managing recurrent croup in pediatric patients.
Methods: We reviewed our REDCap Pediatric Aerodigestive Database for patients with recurrent croup who underwent coordinated endoscopy between January 2013 and July 2023. We reviewed patient demographics, comorbidities, surgical findings, treatments, and outcomes.
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