AI Article Synopsis
- Malherbe tumors, or pilomatricomas, are benign tumors that originate from hair matrix and can occur in the head and neck region.
- A 14-month-old baby had two lesions, one with significant ulceration, prompting an excisional biopsy for diagnosis.
- The histopathological analysis indicated pilomatricoma, but the ulcerated lesion showed increased mitosis, raising concerns for possible pilomatrix carcinoma, suggesting the need for careful monitoring of aggressive behavior in such cases.
Article Abstract
Background: Malherbe tumors, also known as pilomatricomas, are benign cutaneous tumors of hair matrix origin.
Objective: To discuss a rare case of multiple pilomatricoma of the head and neck region in a very young patient.
Methods: A 14-month-old baby presented with two lesions, one appearing on the preauricular region and the other on the nasolabial fold. One of the lesions showed significant ulceration.
Results: Excisional biopsy was performed for both of the lesions. Although the histopathologic examination suggested pilomatricoma as the diagnosis, the lesion with ulcerations exhibited increased mitosis which made us consider pilomatrix carcinoma in its differential diagnosis.
Conclusion: Increased mitoses, an uncommon unexpected feature for pilomatricoma, can be a marker for more aggressive biologic behavior.
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