Although the antimicrobial effects of silver salts were noticed long ago, the molecular mechanism of the bactericidal action of Ag(+) in low concentrations has not been elucidated. Here, we show that low concentrations of Ag(+) induce a massive proton leakage through the Vibrio cholerae membrane, which results in complete deenergization and, with a high degree of probability, cell death.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127333 | PMC |
| http://dx.doi.org/10.1128/AAC.46.8.2668-2670.2002 | DOI Listing |
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