AI Article Synopsis
- A 36-year-old woman with long-standing plaque psoriasis showed significant improvement after having her multinodular goitre surgically removed.
- Post-surgery, she was started on thyroxine and did not have thyroid-related issues, maintaining normal thyroid function and calcium levels.
- Four weeks after surgery, her psoriasis responded much better to narrow-band ultraviolet B therapy compared to before the surgery, suggesting a potential link between thyroid health and psoriasis management that needs more research.
Article Abstract
A 36-year-old Chinese female with an 8-year history of chronic, generalized plaque psoriasis demonstrated a marked improvement of the disease after removal of an intercurrent euthyroid multinodular goitre. Thyroxine was commenced immediately postoperatively. No thyroid antibodies were detected and thyroid function and calcium levels remained within normal limits both pre- and postoperatively. Four weeks following surgery, narrow-band ultraviolet B (nbUVB) therapy was recommenced for recurrent psoriasis. The manifestations of psoriasis at this stage were less severe than before thyroidectomy and responded well to treatment, whereas before surgery the response to therapy had been poor. One year following total thyroidectomy, the patient received very effective psoriasis control with nbUVB therapy. The possible role of surgery and thyroid hormones in altering the pathogenesis of psoriasis in the acute setting is clearly of interest and warrants further research consideration.
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| http://dx.doi.org/10.1046/j.1440-0960.2002.00599.x | DOI Listing |
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