The performance of a novel, rapid, and sensitive test for detecting chemical toxicants in water is described in this article. The bioassay utilizes a highly sensitive variant of the luminescent bacterium Photobacterium leiognathi that allows the detection in water at levels below milligrams per liter of diverse groups of toxicants, including heavy metals, pesticides, PCBs, polycyclic aromatic hydrocarbons, and fuel traces. For most toxic agents reported in this study, the new assay was markedly more sensitive than the Microtox(trade mark) Vibrio fischeri assay according to the bacterial bioluminescence toxicity data reported in the literature. Additional features of the new bioassay include the ability to discriminate between cationic heavy metals and organic toxicants and the option of being run at ambient temperatures (18 degrees C-27 degrees C), thereby enabling on-site testing with low-cost luminometers. In addition, the stability of the freeze-dried bacterial reagent preparation at ambient temperatures precludes the need for refrigeration or freezing during shipment, which contributes to further reducing overall operational costs.
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http://dx.doi.org/10.1002/tox.10060 | DOI Listing |
Invest Radiol
January 2025
From the Department of Radiology, Ulsan University Hospital, Ulsan, Republic of Korea (T.Y.L.); Department of Radiology, University of Ulsan College of Medicine, Seoul, Republic of Korea (T.Y.L.); Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea (J.H.Y., H.K., J.M.L.); Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea (J.H.Y., S.H.P., J.M.L.); Department of Radiology, Inje University Busan Paik Hospital, Busan, Republic of Korea (J.Y.P.); Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea (S.H.P.); Department of Radiology, Hanyang University College of Medicine, Seoul, Republic of Korea (C.L.); Division of Biostatistics, Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea (Y.C.); and Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea (J.M.L.).
Objective: The aim of this study was to intraindividually compare the conspicuity of focal liver lesions (FLLs) between low- and ultra-low-dose computed tomography (CT) with deep learning reconstruction (DLR) and standard-dose CT with model-based iterative reconstruction (MBIR) from a single CT using dual-split scan in patients with suspected liver metastasis via a noninferiority design.
Materials And Methods: This prospective study enrolled participants who met the eligibility criteria at 2 tertiary hospitals in South Korea from June 2022 to January 2023. The criteria included (a) being aged between 20 and 85 years and (b) having suspected or known liver metastases.
Adv Skin Wound Care
January 2025
Li-li Ma, MSc, RN, is PhD Candidate, Medical College, Tongji University, Shanghai, China Department of Nursing, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China. Ya-juan Zhang, MSc, RN, is Head Nurse, Department of Nursing, Shanghai Sixth People's Hospital, School of Medicine, Jiao Tong University, Shanghai. Hui-ren Zhuang, MSc, RN, is Department Head Nursing, Department of Nursing, Shanghai East Hospital, School of Medicine, Tongji University. Hui Jiang, PhD, RN, is Nursing Director, Department of Nursing, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University.
Objective: To analyze the risk factors for peristomal skin complications (PSCs) in patients with colorectal cancer and an ostomy, construct a prediction model, and verify its effectiveness.
Methods: In this cross-sectional study, researchers recruited 265 patients with an ostomy at the stoma clinic of a tertiary hospital, from May 2022 to August 2023. Patients were divided into two groups: complications group (n = 81) and no complications group (n = 184).
PLoS One
January 2025
Department of Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Background: Traditional childhood uvulectomy (TCU) is an unregulated cultural practice associated with significant health risks, including infections, anemia, aspiration, and oral or pharyngeal injuries. The reuse of unsafe tools such as blades, needles, or thread loops exacerbates the spread of infectious diseases like HIV and hepatitis B. Despite its clinical significance, the pooled prevalence and associated factors of TCU have not been adequately examined through systematic reviews or meta-analyses.
View Article and Find Full Text PDFWiad Lek
January 2025
DEPARTMENT OF GENERAL PATHOLOGY AND FORENSIC MEDICINE, COLLEGE OF MEDICINE, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: To evaluate the expression levels of SOX-10 in tissues of bladder tumor and to prove the correlation between SOX-10 expression and clinicopathological characteristics of bladder tumors, including patient age, sex, tumor grade, and muscle invasion.
Patients And Methods: Materials and Methods: Forty formalin fixed paraffin embedded FFPE tissue blocks gathered by transurethral resection of bladder tumor are collected from teaching hospitals at Al-Najaf governorate. Those blocks were stained by hematoxylin and eosin.
Wiad Lek
January 2025
DEPARTMENT OF GENERAL PATHOLOGY AND FORENSIC MEDICINE, COLLAGE OF MEDICINE, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: To analyze expression levels of GATA-3 in bladder tumor tissues and to prove a relation between expression of GATA-3 and clinicopathological characteristics of bladder tumors, including patient age, sex, tumor grade, and muscle invasion.
Patients And Methods: Materials and Methods: Forty formalin fixed paraffin embedded (FFPE) tissue blocks obtained from bladder tumor by transurethral resection are collected from teaching hospitals at Al-Najaf governorate. Those blocks are stained by using hematoxylin and eosin stain.
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