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Anti-dengue viral activity of Glycyrrhiza glabra roots in Vero cells.
Sci Rep
October 2024
Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Despite being a global public health problem, there are no antiviral agents for dengue. Plants are the sources of most approved drugs and many phytochemicals have exhibited in vitro antiviral activity. We explored the antiviral potential of the aqueous extract of Glycyrrhiza glabra roots (GGaq) on dengue viruses.
View Article and Find Full Text PDFDissimilar effect of organometallic ruthenium complexes on the viability of MDR and non-MDR experimental models.
J Inorg Biochem
August 2024
Division of Materials Chemistry, Ruđer Bošković Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Electronic address:
Ruthenium complexes containing triphenylphosphine diamide ligands were prepared, characterized, and tested for their biological activity against various cancer cell lines and the malaria parasite, Plasmodium falciparum. The effect of M (mono-substituted) and B (bis-substituted) complexes on the human cervical carcinoma (HeLa) cell line was investigated using the MTT assay. Five (B2, B3, B5, B6, and B13) of the 24 synthesized ruthenium complexes showed significant effects with IC values ranging between 0.
View Article and Find Full Text PDFCarbon nanotube supported cobalt nickel sulphide nano-catalyst for degradation of chloroquine phosphate with peroxymonosulphate.
Environ Technol
November 2024
College of Forestry, Northeast Forestry University, Harbin, People's Republic of China.
Carbon nanotubes supported cobalt nickel sulphide nanoparticles (nano-NiCoS@CNTs) were successfully prepared by a hydrothermal method as heterogeneous catalyst which can be used as an activator of peroxymonosulphate (PMS) for the degradation of chloroquine phosphate (CQP). Based on characterisation techniques, the prepared catalyst has excellent surface properties and structural stability. When different concentrations of CQP were treated with 0.
View Article and Find Full Text PDFRemoval Performance and Mechanism of Emerging Pollutant Chloroquine Phosphate from Water by Iron and Magnesium Co-Modified Rape Straw Biochar.
Molecules
April 2023
School of Environmental and Materials Engineering, Yantai University, Yantai 264005, China.
Chloroquine phosphate (CQP) is effective in treating coronavirus disease 2019 (COVID-19); thus, its usage is rapidly increasing, which may pose a potential hazard to the environment and living organisms. However, there are limited findings on the removal of CQP in water. Herein, iron and magnesium co-modified rape straw biochar (Fe/Mg-RSB) was prepared to remove CQP from the aqueous solution.
View Article and Find Full Text PDFRanking the risks of eighty pharmaceuticals in surface water of a megacity: A multilevel optimization strategy.
Sci Total Environ
June 2023
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China; College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China. Electronic address:
Pharmaceuticals in freshwater posed ecological risks to aquatic ecosystem, however, most risk assessments of pharmaceuticals were conducted at screening level, which were limited by the availability of the toxicity data. In this study, risks of 80 pharmaceuticals including 35 antibiotics, 13 antiviral drugs, 13 illicit drugs, and 19 antidepressants in surface water of Beijing were assessed with a proposed multilevel environmental risk optimization strategy. Target pharmaceuticals were detected in surface water samples with the detection frequency from 1.
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