D1S1171: a new highly variable short tandem repeat polymorphism.

Int J Legal Med

Department of Forensic Medicine, Karl-Franzens-Universität, Universitätsplatz 4, 8010 Graz, Austria.

Published: June 2002

This study reports the evaluation of the STR locus D1S1171 (GDB: 312934) for forensic purposes, which was investigated by PCR amplification and native polyacrylamide gel electrophoresis in 141 unrelated Austrians. No deviations from Hardy-Weinberg expectations were observed. The mean exclusion chance (MEC) was 0.677, the discriminating power (DP) was 0.951 and the observed heterozygosity rate was 0.853. An allelic ladder consisting of 10 sequenced alleles (96-132 bp) was constructed. Sequence analysis revealed a GAAA repeat motif. According to the number of tetranucleotide repeats the smallest allele was designated 9 and the largest allele 18.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00414-001-0267-6DOI Listing

Publication Analysis

Top Keywords

d1s1171 highly
4
highly variable
4
variable short
4
short tandem
4
tandem repeat
4
repeat polymorphism
4
polymorphism study
4
study reports
4
reports evaluation
4
evaluation str
4

Similar Publications

MiniSTR multiplex systems based on non-CODIS loci for analysis of degraded DNA samples.

Forensic Sci Int

November 2007

Department of Legal Medicine, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, Nagano 390-8621, Japan.

We describe two short amplicon autosomal short tandem repeat (miniSTR) quadruplex systems for eight loci D1S1171, D2S1242, D3S1545, D4S2366, D12S391, D16S3253, D20S161, and D21S1437, unlinked from the combined DNA index system (non-CODIS) loci, using newly designed primer sets. The results of an assay of 411 Japanese individuals showed that polymerase chain reaction (PCR) products within the eight loci were less than 150bp in size, without the seven additional bases for adenylation. The frequency distributions in the loci showed no deviations from Hardy-Weinberg equilibrium expectations.

View Article and Find Full Text PDF

D1S1171: a new highly variable short tandem repeat polymorphism.

Int J Legal Med

June 2002

Department of Forensic Medicine, Karl-Franzens-Universität, Universitätsplatz 4, 8010 Graz, Austria.

This study reports the evaluation of the STR locus D1S1171 (GDB: 312934) for forensic purposes, which was investigated by PCR amplification and native polyacrylamide gel electrophoresis in 141 unrelated Austrians. No deviations from Hardy-Weinberg expectations were observed. The mean exclusion chance (MEC) was 0.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!