An Emerging Field in Bioscience High Hydrostatic Pressure Study.

The goal of this mini review is to explain how hydrostatic pressure acts on bio-macromolecules(mainly on protein), giving some basic knowledge. Moreover, it will be shown that high pressure is a powerful tool both for the study of bio-macromolecules such as protein conformation, protein-protein (or protein-nucleic acid, or protein-ligands) interactions and the modulation of enzymatic activity etc. and for study of biotechnological application.