AI Article Synopsis
- The article details the total synthesis of stevastelin B, a new 15-membered cyclic depsipeptide.
- The fatty acid part was obtained stereoselectively from L-quebrachitol and transformed into an amino carboxylic acid.
- The cyclic structure was created using Shioiri's method for macrolactamization.
Article Abstract
The total synthesis and an unambiguous structure confirmation of stevastelin B 1, a novel 15-membered cyclic depsipeptide, are described; the fatty acid moiety in 1, prepared stereoselectively from L-quebrachitol was converted into the amino carboxylic acid, whose macrolactamization by Shioiri's procedure effectively constructed the cyclic structure of 1.
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| http://dx.doi.org/10.1039/b202298b | DOI Listing |
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