Asymmetric hydrogenation of dehydrodipeptides bearing different protecting groups.

Amino Acids

Institut für Organische Katalyseforschung, Universität Rostock e.V., Buchbinderstrasse 5-6, D-18055 Rostock, Germany.

Published: June 2002

N-[(Z)-N-Benzoyl- or N-boc-(2-fluorophenyl)dehydroalanyl]-(R)- or (S)-phenyl-alanines 1,2,5 and 6 were hydrogenated in the presence of chiral and achiral rhodium complexes. The optical induction is compared to the results obtained using the corresponding esters as substrates.

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http://dx.doi.org/10.1007/s007260200018DOI Listing

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