AI Article Synopsis
- A new method is introduced for assessing the uncertainty in alanine EPR transfer dosimetry, specifically in therapeutic radiation doses of 1-5 Gy.
- The evaluation combines experimental data on EPR signal consistency, Type B uncertainty estimates, and Monte Carlo simulations using linear regression techniques.
- Results indicate that alanine dosimetry is reliable for transfer dosimetry within this dose range, achieving overall uncertainties between 1.5% and 4% depending on several factors like the dose and calibration session length.
Article Abstract
A method for evaluating the overall uncertainty of alanine EPR transfer dosimetry in the therapeutic dose range is described. The method uses experimental data on EPR signal reproducibility from replicate dosimeters irradiated to low doses (1-5 Gy), estimates of Type B uncertainties, and Monte Carlo simulations of heteroscedastic orthogonal linear regression. A Bruker ECS106 spectrometer and Bruker alanine dosimeters have been used for this evaluation. The results demonstrate that alanine dosimetry can be used for transfer dosimetry in that range with the overall uncertainty 1.5-4% (1sigma) depending on the dose, the number of replicate dosimeters. and the duration of the calibration session (the session should not exceed one working day).
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| http://dx.doi.org/10.1016/s0969-8043(01)00271-8 | DOI Listing |
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