Multiple linear regression analysis was used to compare the regression coefficients for Australia and Canada on the association between tuberculosis (TB) rates among migrants and the estimated incidence in the country of birth. Regression coefficients predicting the rate of TB among migrants based on the incidence of TB in the country of birth are not significantly different between populations of migrants in Australia and Canada. Our findings support the ability of the incidence of TB in the country of birth to predict variation in the incidence of TB in migrants groups in two migration receiving countries. This information can be used to focus TB treatment and prevention efforts towards high-risk groups.
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Science
January 2025
Department of Biology & Leverhulme Centre for Nature Recovery, University of Oxford, Oxford, UK.
The impacts of degradation and deforestation on tropical forests are poorly understood, particularly at landscape scales. We present an extensive ecosystem analysis of the impacts of logging and conversion of tropical forest to oil palm from a large-scale study in Borneo, synthesizing responses from 82 variables categorized into four ecological levels spanning a broad suite of ecosystem properties: (i) structure and environment, (ii) species traits, (iii) biodiversity, and (iv) ecosystem functions. Responses were highly heterogeneous and often complex and nonlinear.
View Article and Find Full Text PDFJ Appl Gerontol
January 2025
Department of Gerontology, Simon Fraser University, Vancouver, BC, Canada.
This scoping review, following Levac et al.'s methodology, examines the implementation and impact of relationship-centered care (RCC) in long-term care (LTC) settings for older adults. Peer-reviewed articles from AgeLine, CINAHL Complete, MEDLINE, PsycINFO, and Web of Science were included if published after 2000, involved older adults in LTC homes, focused on RCC, and conducted in Australia, Europe, New Zealand, or North America.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Molecular Imaging & Therapy, Austin Health, Heidelberg, VIC, Australia.
Background: Tau PET is instrumental in tracking the longitudinal progression of Alzheimer's disease (AD). F-MK6240 is a high affinity tracer targeting the 3R/4R paired helical filaments of tau in AD. We aimed to evaluate the early phase of the natural progression of tau accumulation using F-MK6240.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX, USA.
Background: Disrupted sleep patterns have been shown to exacerbate Alzheimer's disease (AD) risk, potentially because of sleep's role in memory consolidation and synaptic plasticity. Recent evidence highlights that high brain-derived neurotrophic factor (BDNF) levels, a protein enabling neuroplasticity and memory functions, could play a protective role in age related cognitive impairment. We examined the association between total sleep time and cognition, and BDNF levels as a potential modifier.
View Article and Find Full Text PDFBackground: Tau phosphorylated at position 217 (pTau217) is considered to have the highest accuracy in identifying Alzheimer's disease (AD) pathology using blood. We describe a multi-cohort evaluation of the Simoa ALZpath pTau217 assay for the prediction of amyloid status in combination with additional blood-based AD biomarkers (GFAP, pTau181, etc.), as well as comparisons between histopathological and PET based amyloid measurements.
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