A method is presented for calculation of a two-dimensional function, T(wedge)(x,y), describing the transmission of a wedged photon beam through a patient. This in an extension of the method that we have published for open (nonwedged) fields [Med. Phys. 25, 830-840 (1998)]. Transmission functions for open fields are being used in our clinic for prediction of portal dose images (PDI, i.e., a dose distribution behind the patient in a plane normal to the beam axis), which are compared with PDIs measured with an electronic portal imaging device (EPID). The calculations are based on the planning CT scan of the patient and on the irradiation geometry as determined in the treatment planning process. Input data for the developed algorithm for wedged beams are derived from (the already available) measured input data set for transmission prediction in open beams, which is extended with only a limited set of measurements in the wedged beam. The method has been tested for a PDI plane at 160 cm from the focus, in agreement with the applied focus-to-detector distance of our fluoroscopic EPIDs. For low and high energy photon beams (6 and 23 MV) good agreement (approximately 1%) has been found between calculated and measured transmissions for a slab and a thorax phantom.
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http://dx.doi.org/10.1118/1.1463064 | DOI Listing |
Phys Med
January 2025
Department of Radiation Oncology, The Third Affiliated Hospital, Sun Yan-Sen University, Guangzhou 510630, China. Electronic address:
A preliminary study was conducted using electronic portal imaging device (EPID) based dose verification in pre-treatment and in vivo dose reconstruction modes for breast cancer intensity-modulated radiation therapy (IMRT) technique with known repositioning set-up errors. For 43 IMRT plans, the set-up errors were determined from 43 sets of EPID images and 258 sets of cone beam computed tomography images. In-house developed Edose software was used to reconstruct the dose distribution using the pre-treatment and on-treatment (in vivo) EPID acquired fluence maps.
View Article and Find Full Text PDFJHEP Rep
November 2024
Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
Background & Aims: MRI guidance offers better lesion targeting for microwave ablation of liver lesions with higher soft-tissue contrast, as well as the possibility of real-time thermometry. This study aims to evaluate the correlation of real-time MR thermometry-predicted lesion volume with the ablation zone in postprocedural first-day images.
Methods: This single-center retrospective analysis evaluated prospectively included patients who underwent MRI-guided microwave ablation with real-time thermometry between December 2020 and July 2023.
Comput Biol Med
December 2024
Faculty of Chemical & Petroleum Engineering, University of Tabriz, Tabriz, Iran. Electronic address:
Background And Objectives: The liver, a vital metabolic organ, is always susceptible to various diseases that ultimately lead to fibrosis, cirrhosis, acute liver failure, chronic liver failure, and even cancer. Optimal and specific medicine delivery in various diseases, hepatectomy, shunt placement, and other surgical interventions to reduce liver damage, transplantation, optimal preservation, and revival of the donated organ all rely on a complete understanding of perfusion and mass transfer in the liver. This study aims to simulate the computational fluid dynamics of perfusion and the temporal-spatial distribution of a medicine in a healthy liver to evaluate the hemodynamic characteristics of flow and medicine transport with the purpose of more effective liver treatment.
View Article and Find Full Text PDFPhys Imaging Radiat Oncol
October 2024
University of Newcastle, University Drive, Newcastle, 2308, New South Wales, Australia.
The aim of this work was to evaluate results of a remote electronic portal imaging based dosimetric auditing method using Task-Group 218 clinical gamma evaluation criteria (3%,2 mm, 10% dose threshold). For intensity modulated radiation therapy the results were (mean ± 1 SD) 97.9 ± 4.
View Article and Find Full Text PDFFront Oncol
December 2024
Medical Physics and Biomedical Engineering Lab (MPBEL), Yonsei University College of Medicine, Seoul, Republic of Korea.
Purpose: This study presents novel quality assurance (QA) approach for volumetric modulated arc therapy (VMAT) that leverages frame-by-frame electronic portal imaging device (EPID) images integrated into Mobius3D for accurate three-dimensional dose calculations.
Methods: Sequential EPID images for VMAT plans were acquired every 0.4-second by iView system and processed through iterative deconvolution to mitigate blurring from photon scattering.
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