The paper presents a comprehensive analysis of the experience gained by the Russian Surgery Research Center over 40 years in improving the qualification of physicians and middle-level medical workers. It outlines teaching methods, shows the efficiency of flexible and mobile technologies in improving the qualification of medical staff, which are based on an individual differential approach to each student and which are oriented to satisfy the needs of a specific health care facility that has sent a specialist to be trained, provides evidence for that it is expedient and effective to improve the qualification of medical staff on the basis of a research institution, by taking into account the fact that the students will introduce new methods and technologies into practical public health care.
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Indian J Thorac Cardiovasc Surg
February 2025
Sechenov First Moscow State Medical University, Moscow, Russia.
Pulmonary arteriovenous malformation (PAVM) is a congenital vascular pathology, which is caused by the presence of a direct connection between the branches of the artery and the veins of the lungs, and the discharge of unoxygenated blood into the arterial bed. Arteriovenous malformations are characterized by a wide variety of clinical manifestations and, in some cases, may be accompanied with severe circulatory disorders.
View Article and Find Full Text PDFOral Maxillofac Surg
January 2025
Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Objective: A nanometer-sized vesicles originating from bone marrow mesenchymal stem cells (BMMSCs), called exosomes, have been extensively recognized. This study defines the impact of BMMSCs and their derived exosomes on proliferation, apoptosis and oxidative stress (OS) levels of CP-induced parotid salivary gland damage.
Methods: BMMSCs were isolated from the tibia of four white albino rats and further characterized by flowcytometric analysis.
Sci Rep
January 2025
Department of Faculty Surgery No. 1, Pirogov Russian National Research Medical University (Pirogov Medical University), Ostrovityanova Str., 1, Moscow, Russia, 117997.
Spontaneous bleeding into soft tissues was a common complication of anticoagulant therapy among critically ill patients during the COVID-19 pandemic. This study sought to evaluate the impact of different treatment methods on survival among COVID-19 patients with active or self-resolved spontaneous bleeding into soft tissues. Methods used to treat CT-confirmed spontaneous hematomas in COVID-19 patients included nonoperative management (NOM), angiography (AG) with transarterial embolization (TAE) and open surgery (OS).
View Article and Find Full Text PDFCurr Med Chem
January 2025
Laboratory of Angiopathology Institute of General Pathology and Pathophysiology, 8, Baltiiskaya Street, 125315, Moscow, Russia.
This review discusses the possibility of inheritance of some diseases through mutations in mitochondrial DNA. These are examples of many mitochondrial diseases that can be caused by mutations in mitochondrial DNA. Symptoms and severity can vary widely depending on the specific mutation and affected tissues.
View Article and Find Full Text PDFJ Spine Surg
December 2024
Department of Neurosurgery, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Background: Currently, there remains a high percentage of complications after lumbar discectomy, while there is no uniform tactic to prevent their development. Purpose of the study was to compare the clinical efficacy and return to work rate (RWR) after total disk replacement (TDR) and microsurgical lumbar discectomy (MLD) in railway workers with lumbar disk herniation (LDH).
Methods: We randomly assigned 75 patients out of a total of 81 patients, between 25 and 35 years of age who had one level LDH to undergo single-level TDR surgery (group I, n=37) or MLD surgery (group II, n=38) in the L4-L5 or L5-S1 segments.
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