Two HTML-based programs were developed to analyze and filter gene-expression data: 'Bullfrog' for Affymetrix oligonucleotide arrays and 'Spot' for custom cDNA arrays. The programs provide intuitive data-filtering tools through an easy-to-use interface. A background subtraction and normalization program for cDNA arrays was also built that provides an informative summary report with data-quality assessments. These programs are freeware to aid in the analysis of gene-expression results and facilitate the search for genes responsible for interesting biological processes and phenotypes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139376PMC
http://dx.doi.org/10.1186/gb-2002-3-6-software0001DOI Listing

Publication Analysis

Top Keywords

cdna arrays
8
software methods
4
methods oligonucleotide
4
oligonucleotide cdna
4
cdna array
4
array data
4
data analysis
4
analysis html-based
4
html-based programs
4
programs developed
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!