AI Article Synopsis
- Perinatal bleeding can result in fatal outcomes in about 10% of cases, highlighting the seriousness of the condition.
- A 29-year-old woman successfully received recombinant activated factor VII during surgery to control severe bleeding after a cesarean section and hysterectomy.
- The use of rFVIIa allowed for rapid control of hemorrhage, enabling safe identification of the source of bleeding without significant clotting issues post-surgery, suggesting its effectiveness in treating life-threatening obstetrical hemorrhages.
Article Abstract
Perinatal bleeding may lead to a fatal outcome in about 10% of cases. We present a case of a 29 year old woman in childbirth, in whom a preparation of recombinant activated factor VII (rFVIIa, NovoSeven, Novo Nordisk A/S, Bagsvaerd, Denmark) was used with success to control intraoperative bleeding during haemorrhagic shock after caesarean section and obstetrical hysterectomy, in the course of the patient's third abdominal cavity revision for continuing blood loss. Administration of the preparation enabled for quick intraoperative control of haemorrhage, which allowed safe and clear identification and elimination of the cause of bleeding. No significant clotting abnormalities were noted at postoperative monitoring of the coagulation system. rFVIIa seems to be an effective alternative treatment of life-threatening haemorrhages in obstetrics, allowing for quick arrest of bleeding, and thus safe control of intraoperative local hemostasis.
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