We prospectively evaluated 52 consecutive cases of newly identified absolute lymphocytosis to determine the hematologic and immunophenotypic features of transient stress lymphocytosis (TSL). The lymphocytosis in all cases was associated with an acute stressful event and ranged from 4,000 to 10,400/microL (4.0-10.4 x 10(9)/L). Compared with healthy individuals, patients with TSL showed an increase in the total WBC, absolute lymphocyte (ALC), absolute neutrophil (ANC), and platelet counts with no difference in hemoglobin levels. Immunophenotypic analyses of 38 cases revealed increases in absolute numbers of T B, and natural killer cells. Both CD4+ and CD8+ T cells were increased, predominantly accountedfor by an increase in memory cell subsets, with no change in gamma/delta T cells. Follow-up studies showed a significant reduction in the ALC with a concurrent increase in the ANC and reduction in hemoglobin values. The reduction in lymphocytes at resolution was accompanied by reduction in all broad Iymphocyte subsets. However, naive and memory subsets showed different patterns of alteration within the CD4+ and CD8+ populations, suggesting that acute stress differentially affects the in vivo distribution of these subsets.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1309/DU0B-EBFL-3EXY-VUFP | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in Artemisia annua.
Sci Rep
December 2024
National & Local United Engineering Laboratory for Chinese Herbal Medicine Breeding and Cultivation, School of Life Sciences, Jilin University, Changchun, Jilin Province, People's Republic of China.
Cold stress, a major abiotic factor, positively modulates the synthesis of artemisinin in Artemisia annua and influences the biosynthesis of other secondary metabolites. To elucidate the changes in the synthesis of secondary metabolites under low-temperature conditions, we conducted dynamic transcriptomic and metabolite quantification analyses of A. annua leaves.
View Article and Find Full Text PDFImpact of COVID-19 on heart rate variability in post-COVID individuals compared to a control group.
Sci Rep
December 2024
Cardiopulmonary Physiotherapy Laboratory, Physical Therapy Department, Universidade Federal de São Carlos, Rodovia Washington Luiz, São Carlos, SP, 13565-905, Brazil.
This study investigated the impact of mild COVID-19 on HRV in groups stratified by time after infection and to compare to a healthy group of the same age without previous virus infection and without need of hospitalization. This is a cross-sectional study. We divided the sample into four groups: control group (CG) (n = 31), group 1 (G1): ≤6 weeks (n = 34), group 2 (G2): 2-6 months (n = 30), group 3 (G3): 7-12 months (n = 35) after infection.
View Article and Find Full Text PDFTopology synthesis of coupled inductor based four port DC-DC converter for multi-input PV-battery application with autonomous mode selection.
Sci Rep
December 2024
Department of Electrical and Electronics Engineering, Dr.N.G.P. Institute of Technology, Coimbatore, India.
Multiport converters are the most reliable and integral component for latest renewable source integration with multiple inputs. This article is one among the kind, which proposes a novel Coupled Inductor based Four Port topology Multiport Converter (CI-FP-MPC) for integrating multiple PV sources with different voltages. The adoption of coupled inductor contributes an increased voltage gain with reduced stress on the switches and diodes.
View Article and Find Full Text PDFThe 1888 dissertation of a female medical student, Ueber Character-Veränderungen des Menschen in Folge von Laesionen des Stirnhirns (On character changes of man as a consequence of lesions of the frontal lobe).
Cortex
November 2024
Neurologische Klinik und Poliklinik, LMU Klinikum, LMU München, Munich, Germany. Electronic address:
A case of brain injury with a transient syndrome of mainly disinhibited behaviour (Franz Binz) was the subject of the 1888 medical dissertation of Leonore Welt (∗1859 Chernivtsi, Ukraine; †1944 Geneva, Switzerland) which came to be discussed quite controversially. Although Binz was never fully forgotten, the similar "American crow-bar case" (Phineas Gage) attracted more interest. Welt's study, in contrast, provides not only well-illustrated neuropathological findings but also more detailed clinical data.
View Article and Find Full Text PDFKey concepts and a world-wide look at plant recruitment networks.
Biol Rev Camb Philos Soc
December 2024
Andalusian Interuniversity Institute for Earth System Research (IISTA), Avenida del Mediterráneo, Granada, 18071, Spain.
Plant-plant interactions are major determinants of the dynamics of terrestrial ecosystems. There is a long tradition in the study of these interactions, their mechanisms and their consequences using experimental, observational and theoretical approaches. Empirical studies overwhelmingly focus at the level of species pairs or small sets of species.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!