Streptococcus pyogenes isolates from a tropical region and a subtropical region of Australia with high and low incidences of severe streptococcal diseases, respectively, were analyzed for speA, speB, and speC gene distributions and NAD-glycohydrolase expression. No direct correlation of these characteristics with a propensity to cause invasive diseases was observed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC120539PMC
http://dx.doi.org/10.1128/JCM.40.7.2642-2644.2002DOI Listing

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