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Detection of Costal Cartilage Fractures on CT Images With Computer-aided Detection System for Rib Fractures.
In Vivo
December 2024
Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan.
Background/aim: Costal cartilage fractures are associated with poor prognosis in patients with blunt chest trauma. A Computer-Aided Detection (CAD) system for detecting rib fractures has been used in practice, but it is unclear whether this system recognizes costal cartilage fractures. This study investigated whether the CAD system for rib fracture can detect costal cartilage fractures.
View Article and Find Full Text PDFOptimal site for applying transcutaneous bilirubinometer as an outpatient screening tool for neonatal jaundice: a comparison between the sternum and forehead.
Front Pediatr
December 2024
Department of Pediatrics, Division of Neonatology, Medical College of Wisconsin, Wauwatosa, WI, United States.
Background: The gold standard for assessing neonatal jaundice (NJ) is the serum total serum bilirubin (TSB) level by the diazo method. A transcutaneous bilirubinometer (TCB) provides a convenient, noninvasive readout within minutes. The reliability of TCB as the diagnostic tool and the proper site for TCB measurement remains unsettled.
View Article and Find Full Text PDFFemoral bone metastasis is a poor prognostic factor in EGFR-TKIs-treated patients with -mutated non-small-cell lung cancer: a retrospective, multicenter cohort study.
Ther Adv Med Oncol
December 2024
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Background: ()-mutant non-small-cell lung cancers (NSCLCs) have higher frequencies of bone metastases than those of wild type; however, the metastatic pattern and influence on clinical outcome remain unclear.
Objectives: To analyze the association between bone metastatic sites and the clinical efficacy of the first-, second-, and third-generation EGFR-tyrosine kinase inhibitors (TKI), in these patients.
Design: Retrospective multicenter cohort study.
Use of epigenetically modified bacteriophage and dual beta-lactams to treat a Mycobacterium abscessus sternal wound infection.
Nat Commun
November 2024
Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA.
Nontuberculous mycobacterium (NTM) infections are challenging to manage and are frequently non-responsive to aggressive but poorly-tolerated antibiotic therapies. Immunosuppressed lung transplant patients are susceptible to NTM infections and poor patient outcomes are common. Bacteriophages present an alternative treatment option and are associated with favorable clinical outcomes.
View Article and Find Full Text PDFArticle Synopsis
- A 75-year-old woman was referred to the hospital due to dizziness, with CT scans revealing generalized lymphadenopathy and a 10 cm tumor in her left kidney, leading to a diagnosis of Hodgkin's lymphoma and left renal cell carcinoma.
- After starting chemotherapy for the lymphoma, metastases from the renal cancer appeared after a year, prompting a shift to combination therapy with Pembrolizumab and Axitinib.
- After experiencing gastritis and severe thrombocytopenia as side effects, treatment was adjusted, and she is currently on Cabozantinib with no recurrence of previous complications.
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