Using the prototype strain of SHF virus, we have confirmed the nature of the genome (RNA), the presence of an envelope (derived from an internal membrane), the virion size (45-50 nm), and probable cubic symmetry. We have also described four viral structural proteins and determined the phospholipid content of the virions. The known properties of SHF virus suggest that it should be classified in the Togavirus family, and possibly in the Flavivirus group.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3181/00379727-150-39111 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hemorrhagic fevers caused by South American Mammarenaviruses: A comprehensive review of epidemiological and environmental factors related to potential emergence.
Travel Med Infect Dis
March 2025
One Health Research Group, Universidad de las Americas, Quito, Ecuador.
South American hemorrhagic fevers (SHF), a group of zoonotic diseases caused by various virus families including Arenaviridae, Bunyaviridae, Filoviridae, and Flaviviridae, are primarily confined to geographic areas where their host species reside. Transmission to humans occurs through direct contact with infected animals, especially rodents, and when infected, humans can transmit diseases to other humans through person-to-person interactions and other means, leading to illnesses that range from mild to life-threatening conditions. Diseases such as Argentine hemorrhagic fever, caused by the Junin virus, Brazilian hemorrhagic fever, caused by the Sabia virus, Venezuelan hemorrhagic fever, caused by the Guanarito virus, and Chapare hemorrhagic fever, are responsible for most hemorrhagic fevers excluding hemorrhagic consequences of diseases such as those caused by dengue.
View Article and Find Full Text PDFCy-1, a major QTL for tomato leaf curl New Delhi virus resistance, harbors a gene encoding a DFDGD-Class RNA-dependent RNA polymerase in cucumber (Cucumis sativus).
BMC Plant Biol
October 2024
Takii & Co. Ltd, Konan, Shiga, 520-3231, Japan.
Background: Tomato leaf curl New Delhi virus (ToLCNDV) (family Geminiviridae, genus Begomovirus) is a significant threat to cucumber (Cucumis sativus) production in many regions. Previous studies have reported the genetic mapping of loci related to ToLCNDV resistance, but no resistance genes have been identified.
Results: We conducted map-based cloning of the ToLCNDV resistance gene in cucumber accession No.
Refractory circulatory failure in COVID-19 patients treated with veno-arterial ECMO a retrospective single-center experience.
PLoS One
April 2024
Department for Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Article Synopsis
- The study analyzed survival rates in 28 COVID-19 patients who required veno-arterial extracorporeal membrane oxygenation (VA-ECMO) due to refractory circulatory failure.
- Results showed varying survival rates based on the indication for VA-ECMO, with pulmonary embolism patients having the highest survival rate (80%), while those with refractory vasoplegia had no survivors.
- The findings emphasize the need for better differentiation between types of acute heart failure and suggest that novel biomarkers like soluble interleukin 2 receptor could aid in this differentiation.
Dysregulation of T Cell Differentiation and the IL17A(+)Foxp3(+)Treg Subset in Chronic Hepatitis B Patients with Hepatitis Flare.
Viral Immunol
March 2023
Department of Infectious Diseases, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
The regulatory T (Treg) and T helper 17 (Th17) cells modulate the immune response in chronic hepatitis B virus (HBV) infection by promoting immune tolerance and restricting liver damage or stimulating inflammatory response and rendering hepatocyte injury. These cells act through signaling transcription factors and secreting cytokines. We aimed to observe the percentages of Treg, Th17 cells, and their messenger RNA (mRNA) level of forkhead box protein 3 (Foxp3) and retinoid orphan receptor γt (RORγt) in the chronic hepatitis B (CHB)-infected group and CHB patients with hepatitis flare (HF).
View Article and Find Full Text PDFIntegrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors.
Comput Struct Biotechnol J
May 2022
Faculty of Science, University of South Bohemia in České Budějovice, Branišovská 1760, České Budějovice 370 05, Czech Republic.
Tick-borne encephalitis virus (TBEV), the most medically relevant tick-transmitted flavivirus in Eurasia, targets the host central nervous system and frequently causes severe encephalitis. The severity of TBEV-induced neuropathogenesis is highly cell-type specific and the exact mechanism responsible for such differences has not been fully described yet. Thus, we performed a comprehensive analysis of alterations in host poly-(A)/miRNA/lncRNA expression upon TBEV infection in human primary neurons (high cytopathic effect) and astrocytes (low cytopathic effect).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!