With the advent of new treatment choices, osteoporosis should no longer be considered an inevitable part of aging but rather a disease that can be treated. This article provides an overview of recent advances in treatment of osteoporosis.
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The Knowledge and Health Belief Model of Osteoporosis Prevention Among Females in Saudi Arabia.
Cureus
December 2024
Family Medicine, Ibn Sina National College for Medical Studies, Jeddah, SAU.
Background Osteoporosis is the most common bone disease in humans, representing a major public health problem affecting women more commonly. The prevalence of osteoporosis in Saudi Arabia is high among females. Thus, the knowledge and Health Belief Model (HBM) of osteoporosis, which can be used to gain an understanding of health behaviors and reasons for non-compliance to osteoprotective recommendations, is necessary.
View Article and Find Full Text PDFBilateral Ovarian Agenesis and Bone Modeling Disease in Pre-puberty Girl With Primary Amenorrhea.
Cureus
December 2024
Department of Obstetrics and Gynecology, Royal Medical Services, Amman, JOR.
Ovarian agenesis (OA) is a rare congenital condition characterized by the absence of one or both ovaries, often associated with chromosomal abnormalities, hormonal imbalances, and structural deformities. The condition is frequently diagnosed in females presenting with primary amenorrhea and delayed sexual development. This case report highlights a unique presentation of bilateral ovarian agenesis in a patient with chromosome X translocation, bone modeling disease, and primary amenorrhea.
View Article and Find Full Text PDFCough-Induced Rib Fracture in a Postmenopausal Woman Without Clinical Evidence of Osteoporosis: A Case Report.
Cureus
December 2024
Department of Community Medicine, College of Medicine, Hawler Medical University, Erbil, IRQ.
Cough-induced rib fractures are rare conditions and are seldom reported in the medical literature. This case involves a 54-year-old postmenopausal woman who experienced a persistent dry cough lasting 16 days, which progressed to acute, localized chest pain in the right hemithorax. Symptoms started after an initial chest infection.
View Article and Find Full Text PDFOsteoporosis Caused by Monoallelic Variant of WNT1 Gene in Four Pediatric Patients.
Am J Med Genet A
January 2025
Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Pediatric patients of autosomal dominant early onset osteoporosis conferred by heterozygous mutation in the WNT1 (OMIM: 615221) were rarely reported, and therapy in pediatrics is relatively inexperienced. The clinical and genotypic characteristics and treatment process of four children with osteoporosis caused by WNT1 monoallelic variation were analyzed. The patients admitted from June 2023 to January 2024.
View Article and Find Full Text PDFThe antiosteoporotic effect of oxymatrine compared to testosterone in orchiectomized rats.
J Orthop Surg Res
January 2025
Medical Physiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Background: Castration of adult male rats led to the development of osteoporosis. Oxidative stress and inflammatory factors have been identified as potential causative factors. Notably, oxymatrine (OMT) possesses potent anti-inflammatory and antioxidant activities.
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