The article analyses data on clinical efficacy of the drug enterol in patients with chronic pancreatitis and chronic atropic gastritis. The use of enterol in a complex therapy has been shown to favour quick dispelling of the pain and dyspeptic syndromes, normalization of stools, elimination of intestinal dysbacteriosis or alleviation of its gravity.
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Clin Pharmacokinet
October 2024
Research and Development Directorate, Gedeon Richter Plc, Budapest, Hungary.
Background: Cariprazine is metabolised mainly by CYP3A4 and to a lesser extent by CYP2D6.
Aim: This study aimed to evaluate the effects of erythromycin, a moderate cytochrome P450 (CYP)3A4 inhibitor, on the pharmacokinetics of cariprazine in male patients with schizophrenia, and to assess the influence of CYP2D6 phenotypes on cariprazine metabolism.
Methods: Forty-two patients received oral doses of 1.
Nutrients
August 2024
TARGID, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium.
Acetate-producing var. strains could exert improved effects on ulcerative colitis, which here, was preclinically evaluated in an acute dextran sodium sulphate induced model of colitis. Nine-week-old female mice were divided into 12 groups, receiving either drinking water or 2.
View Article and Find Full Text PDFAppl Environ Microbiol
June 2024
NovelYeast bv, Bio-Incubator BIO4, Leuven-Heverlee, Belgium.
Appl Microbiol Biotechnol
January 2024
Excellent Research Laboratory for Yeast Innovation, Division of Biochemical Technology, School of Bioresources and Technology, King Mongkut's University of Technology Thonburi, Bangkok, Thailand.
Evolutionary engineering experiments, in combination with omics technologies, revealed genetic markers underpinning the molecular mechanisms behind acetic acid stress tolerance in the probiotic yeast Saccharomyces cerevisiae var. boulardii. Here, compared to the ancestral Ent strain, evolved yeast strains could quickly adapt to high acetic acid levels (7 g/L) and displayed a shorter lag phase of growth.
View Article and Find Full Text PDFSaudi J Biol Sci
January 2021
Department of General and Environmental Microbiology, University of Pécs, Faculty of Sciences, Pécs, Hungary.
This study investigated the effect of propolis ethanolic extract (PEE) on planktonic growth and biofilm forming abilities of five commercial probiotics (Enterol, Protexin, Normaflore, BioGaia and Linex). Broth microdilution method was used to investigate the susceptibility of the microbes of five commercial probiotics to PEE. Crystal violet assay was used for the quantitative assessment of biofilm formation and mature biofilm eradication tests.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!