A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Treatment of scleroderma skin ulcers using becaplermin gel and hydrocolloid membrane. | LitMetric

AI Article Synopsis

  • Skin ulcers in patients with systemic sclerosis can be severely painful and challenging to treat.
  • A case study shows that using becaplermin gel along with oral immunosuppressive agents effectively treats these ulcers, with healing times around 3 months.
  • The treatment's success was comparable to other oral medications and specialized surgical options, with no major surgeries needed except for a biopsy.

Article Abstract

Skin ulcers can be very painful and detrimental in patients with systemic sclerosis, or systemic scleroderma. A brief review of scleroderma skin ulcers is presented, as well as a case study that demonstrates the effectiveness of becaplermin gel supplemented by oral immunosuppressive agents in the treatment of ulcers resulting from systemic sclerosis. The time to healing (approximately 3 months) was comparable to that associated with the oral agents and surgical interventions specifically designed to help heal scleroderma ulcers. Except for incisional biopsy, no surgical procedures were performed.

Download full-text PDF

Source
http://dx.doi.org/10.7547/87507315-92-6-350DOI Listing

Publication Analysis

Top Keywords

skin ulcers
12
scleroderma skin
8
becaplermin gel
8
systemic sclerosis
8
ulcers
5
treatment scleroderma
4
ulcers becaplermin
4
gel hydrocolloid
4
hydrocolloid membrane
4
membrane skin
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!