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Nocardiosis in Renal Allograft Recipients.
J Glob Infect Dis
December 2024
Department of Nephrology, Christian Medical College, Vellore, Tamil Nadu, India.
Introduction: The aim of the study was to study the clinical profile and outcomes of nocardiosis in renal allograft recipients.
Methods: This was a retrospective study of clinical outcomes in consecutive renal allograft recipients with infection over a 22-year period (2000-2022) from a tertiary care center in Southern India. The clinical data were obtained from electronic medical records and patient files.
Preparation and evaluation of T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology.
Front Cell Infect Microbiol
January 2025
Jiangsu Engineering Research Center of Biological Data Mining and Healthcare Transformation, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Introduction: Brucellosis, a significant zoonotic infectious disease, poses a global health threat. Accurate and efficient diagnosis is crucial for prevention, control, and treatment of brucellosis. VirB proteins, components of the Type IV secretion system (T4SS) in , play a pivotal role in bacterial virulence and pathogenesis but have been understudied for their diagnostic potential.
View Article and Find Full Text PDFImpact of trypanosomiasis on male camel infertility.
Front Vet Sci
January 2025
Zoology and Entomology Department, Faculty of Science, New Valley University, El-Kharga, Egypt.
Introduction: Blood parasitism is a significant clinical disease that silently undermines the livestock industry, particularly affecting camels. This study aimed to assess the prevalence of in Arabian camels () and its impact on infertility by examining serum protein fractions, lipids, reproductive indices, and the expression of heat shock protein (HSP70) during breeding season.
Methods: A total of 107 male post-pubertal camels, aged between 5 and 10 years, were collected randomly from slaughtering house in Assiut Governorate, Egypt.
An electrochemical nano-genosensor for SARS-CoV-2 detection utilizing Ce-metal organic framework, dendritic palladium nano-structure, and sulfur-doped graphene oxide.
Talanta
January 2025
Enzyme Technology Laboratory, Department of Biochemistry, Genetic and Metabolism Research Group, Pasteur Institute of Iran, 13169-43551, Tehran, Iran. Electronic address:
The emergence of COVID-19 has underscored an urgent demand to develop an innovative, rapid, and reliable diagnostic tool for early detection of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Biosensors present a viable alternative, offering reliability, precision, and cost efficiency that address the limitations of current molecular and serological detection methods, thus facilitating timely identification of COVID-19. In this study, a novel nano-genosenor platform fabricated using advanced nanomaterials based on Ce-metal organic framework (Ce-MOF), dendritic palladium nano-structure (Den-PdNS), and sulfur-doped reduced graphene oxide (S-rGO) for detection of RNA-dependent RNA polymerase (RdRp) SARS-CoV-2 gene targets.
View Article and Find Full Text PDFSensitivity of anti-filarial antibodies for lymphatic filariasis surveillance: Insights from a serological survey in Samoa in 2018.
PLoS Negl Trop Dis
January 2025
UQ Centre for Clinical Research, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Background: Sensitive diagnostic tools that signal lymphatic filariasis (LF) transmission are needed to monitor the progress of LF elimination programs. Anti-filarial antibody (Ab) markers could be more sensitive than antigen (Ag) point-of-care tests for monitoring LF transmission in some settings. This study aimed to investigate the sensitivity of anti-filarial Abs for detecting signals of LF transmission in Samoa by i) investigating the sensitivity and specificity of Ab to identify Ag-positives; ii) estimating the average number needed to test (NNTestav) to identify LF-seropositives (seropositive for Ag and/or any Ab), and iii) compare the efficiency of the different serological indicators by target age group and sampling design.
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