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To evaluate the safety of alpha-glycerylphosphorylcholine (α-GPC) as a novel food, the study of acute oral toxicity, subchronic toxicity, teratogenic toxicity and genotoxicity were conducted. In acute oral toxicity, no toxic effects were observed in rats of both genders administrated 10.0 g/kg BW α-GPC.

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Efficient strategy for employing HN-AD bacterium enhanced biofilter reactors to remove NH and reduce secondary pollution.

J Hazard Mater

December 2024

CAS Key Laboratory of Environmental and Applied Microbiology, Environmental Microbiology Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China. Electronic address:

Article Synopsis
  • - The study focused on using the Heterotrophic nitrification-aerobic denitrification strain Paracoccus denitrificans HY-1 in a biological trickling filter (BTF) reactor to improve ammonia (NH) removal efficiency, achieving a high rate of 96.52% under specific conditions.
  • - Results showed that after inoculation with HY-1 and using bamboo charcoal as filler, levels of ammonia and other nitrogen compounds in the circulating fluid were significantly low, indicating effective nitrification and denitrification processes.
  • - The HY-1 inoculated BTF was tested in a large-scale piggery setting, successfully removing 99.61% of ammonia and 96.63% of hydrogen
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Background: Poisoning is a significant health hazard and a leading cause of morbidity and mortality worldwide. India, being a predominantly agrarian country, routinely employs organophosphate (OP) pesticides in farming, and they are readily available "over the counter." OPs exert their toxicity by interfering with the normal function of acetylcholine, an essential neurotransmitter throughout the autonomic and central nervous systems.

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This is the first successful report on selenium bio-attenuation to satisfy drinking water regulations as per Indian Standards (10 μg/L) in the presence of concomitant nitrate and sulfate from water sources utilizing a fixed bed bioreactor. The bioreactor was immunized with blended microbial culture and worked in downflow mode under anoxic conditions at 30 ± 2 °C for around 190 days under varying influent selenate (100-500 μg/L as selenium), nitrate (50 mg/L), sulfate concentrations (as per selenium removal) and necessary dose of acetic acid (as COD, a carbon source) in synthetic groundwater, operated at an empty bed contact time (EBCT) of 45-120 min. After supplying an adequate dosage of sulfate and alteration of EBCT, selenium was found to comply with drinking water regulations and nitrate was completely removed.

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