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Application of mean maximum Young's modulus value as a new parameter for differential diagnosis of prostate diseases.
Sci Rep
January 2025
Jun Shi Department of Ultrasound, The First Hospital of Hebei Medical University, Shijiazhuang City, 050031, Hebei Province, China.
Transrectal shear wave elastography (T-SWE) can be used non-invasively to diagnose prostate cancer (PCa) and benign prostatic hyperplasia (BPH). The prostate tissue can be viewed as an ellipsoidal sphere with viscoelastic characterization. Linear elastic model has been used to characterize soft tissues, and the simplification of partial characterization provides incomplete information.
View Article and Find Full Text PDFRamp Protocol for Non-linear Cerebrovascular Reactivity with Transcranial Doppler Ultrasound.
J Neurosci Methods
January 2025
IBME, Department of Engineering Science, University of Oxford, Oxford UK.
Background: Cerebrovascular reactivity (CVR) reflects the ability of cerebral blood vessels to adjust their diameter in response to vasoactive stimuli, which is crucial for maintaining brain health. Traditional CVR assessments commonly use a two-point measurement, assuming a linear relationship between cerebral blood flow (CBF) and arterial CO. However, this approach fails to capture non-linear characteristics, particularly the plateaus at extreme CO levels.
View Article and Find Full Text PDFAssociations of the triglyceride-glucose index and remnant cholesterol levels with the prevalence of Carotid Plaque in patients with type 2 diabetes: a retrospective study.
Lipids Health Dis
January 2025
Department of Endocrinology, The Second Affiliated Hospital of Anhui Medical University, Hefei Anhui, 230601, China.
Background: The triglyceride-glucose (TyG) index has been identified as an alternative biomarker for insulin resistance (IR), while residual cholesterol (RC) is a simple, cost-effective, and easily detectable lipid metabolite. However, the associations of these two markers with carotid plaque presence remain unclear. Thus, this study aimed to explore their associations with carotid plaque presence.
View Article and Find Full Text PDFThe obesity paradox in osteoporosis risk among older adults is mostly driven by women: a population-based prospective study.
BMC Geriatr
January 2025
Department of Gerontology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Objectives: The obesity paradox is common among older adults at risk for various diseases. Although this paradox has also been observed in the association between obesity and osteoporosis, the available evidence remains controversial. This study aimed to investigate the association between obesity and OP risk in an older population.
View Article and Find Full Text PDFQuantifying natural amyloid plaque accumulation in the continuum of Alzheimer's disease using ADNI.
J Pharmacokinet Pharmacodyn
January 2025
Global PK/PD/PMx, Eli Lilly and Company, 8 Arlington Square West, Downshire Way, Bracknell, Berkshire, RG12 1PU, UK.
Brain amyloid beta neuritic plaque accumulation is associated with an increased risk of progression to Alzheimer's disease (AD) [Pfeil, J., et al. in Neurobiol Aging 106: 119-129, 2021].
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