Orthodontic records-study models, panoramic and cephalometric radiographs, and the patient's facial and intraoral photographs-are used to collect data to establish a diagnosis and to develop problem-solution lists. These records, however, can be damaged or lost when dispensed to students and need to be stored and maintained every year. An orthodontic diagnosis web site, therefore, has been set up using digital records to provide students with an accessible source of complete, good-quality study materials. The web site is also used for clinical examination in orthodontic courses. The effectiveness of the web-based digital records in providing relevant information to students in comparison to the traditional records was evaluated by a randomized controlled trial involving ninety-nine second-year dental students. One group (fifty students) studied two cases from the web site; the other group (forty-nine students) studied the same two cases from traditional orthodontic records. Effectiveness was assessed by comparing test scores and the time spent on the tests by t-statistics. There were no significant differences between means for the two study groups in test performance or time. Attitudes of students toward the web site, assessed from post-test questionnaires, were positive. It was concluded that web-based digital orthodontic records were as effective in teaching clinical orthodontic diagnosis as were conventional records.
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Heliyon
December 2024
Research Laboratory for Biomechanics and Implant Technology, Department of Orthopaedics, Rostock University Medical Center, Rostock, Germany.
Subject-specific finite element (FE) modeling of the mandible bone has recently gained attention for its higher accuracy. A critical modeling factor is including personalized material properties from medical images especially when bone quality has to be respected. However, there is no consensus on the material model for the mandible that realistically estimates the Young's modulus of the bone.
View Article and Find Full Text PDFFront Public Health
December 2024
Physical Education Institute, Shanxi University, Taiyuan, China.
Purpose: To systematically evaluate the effects of mind-body exercise on physical ability, mental health and quality of life in stroke patients.
Methods: According to the PRISMA statement, we searched Web of science, Pubmed, Embase, Sinomed, CNKI, Wanfang, and VIP databases to collect randomized controlled trials on the effects of mind-body exercise on improving balance function, motor capacity, walking function, depression and quality of life in stroke patients. The search was conducted in January 2024.
J Biomol Struct Dyn
January 2025
Biochemistry and Bioinformatics Laboratory, Department of Applied Sciences, Indian Institute of Information Technology Allahabad (IIIT-A), Prayagraj, Uttar Pradesh, India.
Methicillin-resistant (MRSA), a major cause of fatalities due to Antimicrobial Resistance (AMR), can act as an opportunistic pathogen despite being part of the normal human flora. MRSA infections, such as skin infections, pneumonia, sepsis, and surgical site infections, have risen significantly, with bloodstream infection cases increasing from 21% in 2016 to 35% in 2020. This surge has prompted research into alternative treatments like nanomaterials, photodynamic therapy, antimicrobial peptides (AMPs), and essential oils (EOs).
View Article and Find Full Text PDFLancet Respir Med
December 2024
Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK. Electronic address:
Background: The goal of cystic fibrosis transmembrane conductance regulator (CFTR) modulators is to reach normal CFTR function in people with cystic fibrosis. Vanzacaftor-tezacaftor-deutivacaftor restored CFTR function in vitro and in phase 2 trials in participants aged 18 years and older resulting in improvements in CFTR function, as measured by sweat chloride concentrations and lung function as measured by spirometry. We aimed to evaluate the efficacy and safety of vanzacaftor-tezacaftor-deutivacaftor compared with standard of care elexacaftor-tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years and older.
View Article and Find Full Text PDFCancer Epidemiol
January 2025
Clinical Epidemiology Program, Instituto Nacional de Câncer (INCA), Rio de Janeiro, Brazil.
Introduction: Cancer has become a public health problem worldwide, affecting individuals of different age groups, including children, young adults and older patients.
Objective: To determine the clinical profile, staging and standard of oncological treatment of the 10 most frequent primary sites of cancer in young patients (< 60 years) vs older patients (≥ 60 years old) diagnosed between 2000 and 2019 in Brazil.
Materials And Methods: This cross-sectional study used data from the secondary database of the Hospital Cancer Registry, available on the web www.
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