Bacillus Calmette-Guérin (BCG) immunotherapy is increasingly being accepted for management of some bladder transitional cell neoplastic lesions. Mild adverse reactions occur frequently. However, an unusual complication of tuberculous epididymitis is reported. A 64-year old man presented with bilateral epididymal mass. Four months earlier he had seven treatments with intravesical BCG instillation (Tokyo 172 strain) for a grade 2 transitional cell carcinoma in situ. Bilateral epididymectomy was performed. Microscopic examination of the epididymis revealed chronic inflammation and necrosis with granulomas and Langhans' giant cells. After the operation, there were no further complications.
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http://dx.doi.org/10.5980/jpnjurol1989.93.580 | DOI Listing |
BMC Microbiol
January 2025
Unidad de Manipulación Genética, Facultad de Ciencias Biológicas, Departamento de Microbiología e Inmunología, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Background: Plastic pollution is a significant environmental problem caused by its high resistance to degradation. One potential solution is polyhydroxybutyrate (PHB), a microbial biodegradable polymer. Mexico has great uncovered microbial diversity with high potential for biotechnological applications.
View Article and Find Full Text PDFJ Biosci Bioeng
January 2025
College of Biological Engineering, Qingdao University of Science and Technology, Qingdao 266045, China.
Straw degradation was slow under low temperature environments. A cold-tolerant consortium LHWA was constructed by Bacillus cereus, Acinetobacter lwoffii, Penicillium griseofulvum, and Talaromyces funiculosus. The consortium and culture conditions were optimized.
View Article and Find Full Text PDFDev Comp Immunol
January 2025
Department of Plant Medicals, College of Life Sciences, Andong National University, Andong 36729, Korea. Electronic address:
Host cabbage possesses an endophyte, Bacillus subtilis, which induced immune-priming of the diamondback moth, Plutella xylostella. In contrast, larvae raised under axenic conditions lost the chance to feed the bacteria and were highly susceptible to various pathogens. Addition of B.
View Article and Find Full Text PDFJ Invertebr Pathol
January 2025
UK Centre for Ecology & Hydrology, Maclean Building, Benson Lane, Crowmarsh Gifford, Wallingford, Oxfordshire OX10 8BB, United Kingdom. Electronic address:
The insect mass-rearing industry to produce feed and food is expanding rapidly. Insects in production frequently encounter multiple pathogens and environmental stressors simultaneously, which can lead to significant economic losses. Our understanding of the interactions between different stressors remains limited, and existing methods primarily focus on determining overall patterns of additivity, synergism, or antagonism.
View Article and Find Full Text PDFUrology
January 2025
Department of Urology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Objective: To evaluate the efficacy, recurrence rates, and safety profile of intravesical gemcitabine plus docetaxel versus standard Bacillus Calmette-Guérin (BCG) therapy for treating naïve non-muscle-invasive bladder cancer (NMIBC), focusing on reducing recurrence and progression concerns associated with transurethral resection (TURBT).
Methods: Relevant articles were identified and appraised through a structured assessment of the literature. Databases searched included PubMed, Medline, Scopus, and Science Direct.
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