Attempts were made to infect 4 species of New World monkeys (Saimiri boliviensis, Aotus nancymai, A. vociferans, A. azarae boliviensis) with Plasmodium gonderi, a malaria parasite of African monkeys. Sporozoites were obtained from Anopheles dirus or A. stephensi mosquitoes that fed on an infected rhesus monkey (Macaca mulatta). Inoculation of sporozoites was by injection of dissected sporozoites by either the intravenous or intrahepatic routes, or by mosquito bite. Liver biopsies done 7 or 8 days after sporozoite inoculation showed that hepatocytes of all 4 species of these New World monkeys supported exoerythrocytic stages of P. gonderi, but daily blood film examination during a 60-day observation period failed to detect blood stages of the parasite.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1645/0022-3395(2002)088[0422:IOAASM]2.0.CO;2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Genome of Plasmodium gonderi: Insights into the Evolution of Human Malaria Parasites.
Genome Biol Evol
February 2024
Biology Department/Institute of Genomics and Evolutionary Medicine (iGEM), Temple University, Philadelphia, PA 19122-1801, USA.
Plasmodium species causing malaria in humans are not monophyletic, sharing common ancestors with nonhuman primate parasites. Plasmodium gonderi is one of the few known Plasmodium species infecting African old-world monkeys that are not found in apes. This study reports a de novo assembled P.
View Article and Find Full Text PDFProgress in understanding the phylogeny of the Plasmodium vivax lineage.
Parasitol Int
April 2022
Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba 305-8572, Japan. Electronic address:
There has been some controversy about the evolutionary origin of Plasmodium vivax, particularly whether it is of Asian or African origin. Recently, a new malaria species which closely related to ape P. vivax was found in chimpanzees, in addition, the host switches of P.
View Article and Find Full Text PDFEcological, parasitological and individual determinants of plasma neopterin levels in a natural mandrill population.
Int J Parasitol Parasites Wildl
April 2020
ISEM, University of Montpellier, CNRS, EPHE, IRD, Montpellier, France.
Investigating how individuals adjust their investment into distinct components of the immune system under natural conditions necessitates to develop immune phenotyping tools that reflect the activation of specific immune components that can be measured directly in the field. Here, we examined individual variation of plasma neopterin, a biomarker of Th1 immunity in wild mandrills (), who are naturally exposed to a suite of parasites, including simian retroviruses and malaria agents. We analyzed a total of 201 plasma samples from 99 individuals and examined the effect of sex, age, social rank, reproductive state and disease status on neopterin levels.
View Article and Find Full Text PDFA longitudinal molecular study of the ecology of malaria infections in free-ranging mandrills.
Int J Parasitol Parasites Wildl
December 2019
Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle UMR, 224-5290, Montpellier, France.
Unravelling the determinants of host variation in susceptibility and exposure to parasite infections, infection dynamics and the consequences of parasitism on host health is of paramount interest to understand the evolution of complex host-parasite interactions. In this study, we evaluated the determinants, temporal changes and physiological correlates of infections in a large natural population of mandrills (). Over six consecutive years, we obtained detailed parasitological and physiological data from 100 male and female mandrills of all ages.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!