The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out. The gene is present in the genome as a single copy and transcribed as a polyadenylated transcript of 830 nucleotides. The deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.
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| http://dx.doi.org/10.1645/0022-3395(2002)088[0199:CAMCOT]2.0.CO;2 | DOI Listing |
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