According to legislation the producer is responsible for the product. Products placed on the market must be safe and the relevant documentation confirming the conformity of the product with the accepted limits of global and specific migration must be available from the producer. The provisions concerning acceptable migration limits (global and specific), stimulants and testing methods are set by the relevant regulations. Distilled water, 3% acetic acid, 10% ethanol and olive oil are used as stimulants of foodstuffs. The choice of an appropriate stimulant and testing conditions depends on the type of food expected to come in contact with packaging. According to provisions testing should be performed in the conditions, which possibly closely reflect actual or expected use of the packaging material, taking into account storage of the product as well as possible thermal processing. Test methods for global migration into stimulants using the cell, pouch, by immerse or by article filling are recommended. The criteria used to choose an appropriate testing method are set in European Standards EN 1186. A product meets the quality criteria as set by the legislation if the global migration from the packaging into stimulants does not exceed value of 10 mg/dm2 or 60 mg/kg and if the specific migration limit (SML), set for given substance is not exceeded.
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IGIE
December 2024
School of Computer Science, University of Oklahoma, Norman, Oklahoma, USA.
Background And Aims: Obesity is a global health concern. Bariatric surgery offers reliably effective and durable weight loss and improvements of other comorbid conditions. However, the accessibility of bariatric surgery remains limited.
View Article and Find Full Text PDFBackground/objectives: Bone marrow (BM) adipocytes are critical in progressing solid tumor metastases and hematological malignancies across pediatric to aging populations. Single-point biopsies remain the gold standard for monitoring BM diseases, including hematologic malignancies, but are limited in capturing the full complexity of loco-regional and global BM microenvironments. Non-invasive imaging techniques like Magnetic Resonance Imaging (MRI), could offer valuable alternatives for real-time evaluation of BM diseases in both preclinical translational and clinical studies.
View Article and Find Full Text PDFUrbanization as a major driver of global change modifies biodiversity patterns and the abundance and interactions among species or functional species groups. For example, urbanization can negatively impact both predator-prey and mutualistic relationships. However, empirical studies on how urbanization modifies biotic, particularly multitrophic, interactions are still limited.
View Article and Find Full Text PDFEcol Evol
January 2025
Conservation Science Research Group, School of Environmental and Life Sciences University of Newcastle Callaghan New South Wales Australia.
Amphibians are among the most threatened vertebrate taxa globally. Their global decline necessitates effective conservation actions to bolster populations across both the larval and adult stages. Constructing man-made ponds is one action proven to enhance reproduction in pond-breeding amphibians.
View Article and Find Full Text PDFAnthropogenic planetary heating is disrupting global alpine systems, but our ability to empirically measure and predict responses in alpine species distributions is impaired by a lack of comprehensive data and technical limitations. We conducted a comprehensive, semi-quantitative review of empirical studies on contemporary range shifts in alpine insects driven by climate heating, drawing attention to methodological issues and potential biotic and abiotic factors influencing variation in responses. We highlight case studies showing how range dynamics may affect standing genetic variation and adaptive potential, and discuss how data integration frameworks can improve forecasts.
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