Effects of the Loach Polysaccharide on Removal of Reactive Oxygen Species and Protection of DNA Chains.

Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)

Pharmaceutical Institute, Huazhong University of Science and Technology, Wuhan 430074, China.

Published: January 2001

The effects of the Misgurnus anguillicaudatus polysaccharide on removal of reactive oxygen species in some modified chemical systems were investigated by chemiluminescence and spectrophotometry. The inhibition of the damage of DNA chain induced by hydroxyl radical by the Misgurnus anguillicaudatus polysaccharide was observed by chemiluminescence. The results showed that the Misgurnus anguillicaudatus polysaccharide could efficiently remove O.(-)(2),.OH, H(2)O(2) and other active compounds of oxygen and significantly protected DNA chains from being damaged by free radicals.

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