AI Article Synopsis
- Acetylation of proteins is a process where acetyl groups are added to specific amino acids, facilitated by enzymes called acetyltransferases.
- Amino-terminal acetylation is common in eukaryotic proteins and regulatory peptides, while lysine acetylation happens at various sites on numerous proteins, including histones and transcription factors.
- This modification plays a crucial role in regulating protein function and interactions within cells.
Article Abstract
Acetylation of proteins, either on various amino-terminal residues or on the epsilon-amino group of lysine residues, is catalyzed by a wide range of acetyltransferases. Amino-terminal acetylation occurs on the bulk of eukaryotic proteins and on regulatory peptides, whereas lysine acetylation occurs at different positions on a variety of proteins, including histones, transcription factors, nuclear import factors, and alpha-tubulin.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139359 | PMC |
| http://dx.doi.org/10.1186/gb-2002-3-5-reviews0006 | DOI Listing |
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