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The motivation for this article stems from the fact that medical image security is crucial for maintaining patient confidentiality and protecting against unauthorized access or manipulation. This paper presents a novel encryption technique that integrates the Deep Convolutional Generative Adversarial Networks (DCGAN) and Virtual Planet Domain (VPD) approach to enhance the protection of medical images. The method uses a Deep Learning (DL) framework to generate a decoy image, which forms the basis for generating encryption keys using a timestamp, nonce, and 1-D Exponential Chebyshev map (1-DEC).

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Revisions of the Phenomenological and Statistical Statements of the Second Law of Thermodynamics.

Entropy (Basel)

December 2024

Istituto Nazionale di Alta Matematica (INdAM), 00185 Rome, Italy.

The status of the Second Law of Thermodynamics, even in the 21st century, is not as certain as when Arthur Eddington wrote about it a hundred years ago. It is not only about the truth of this law, but rather about its strict and exhaustive formulation. In the previous article, it was shown that two of the three most famous thermodynamic formulations of the Second Law of Thermodynamics are non-exhaustive.

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Glaciers provide multiple ecosystem services (ES) to human society. Due to the continued global warming, the valuation of glacier ES is of urgent importance because this knowledge can support the protection of glaciers. However, a systematic valuation of glacier ES is still lacking, particularly from the perspective of ES contributors.

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Application of model-informed drug development (MIDD) for dose selection in regulatory submissions for drug approval in Japan.

J Pharmacokinet Pharmacodyn

January 2025

Clinical Pharmacology Development Area, MSD K.K., Tokyo, Japan.

Model-informed drug development (MIDD) is an approach to improve the efficiency of drug development. To promote awareness and application of MIDD in Japan, the Data Science Expert Committee of the Drug Evaluation Committee in the Japan Pharmaceutical Manufacturers Association established a task force, which surveyed MIDD applications for approved products in Japan. This study aimed to reveal the trends and challenges in the use of MIDD by analyzing the survey results.

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The article describes a technique for digital holographic reconstruction of complex amplitude fields in diffuse blood facies using laser polarization-interference phase scanning to isolate a single scattered component of the object field. This method serves as the basis for developing algorithms for Mueller-matrix reconstruction of linear and circular birefringence parameters in the polycrystalline architectonics of blood facies. Statistical (central moments of the 1st-4th orders) and multifractal analyses (fractal dimension spectra) are applied to study the optical anisotropy maps of polycrystalline networks during blood dehydration.

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