The dynamic of a series of responses for four pigeons is analyzed using a discrete fast Fourier transform (FFT) and a measure of behavior's predictability. FFTs of moment-to-moment response rates reliably exhibited a continuous distribution for three of the four birds, with most of the power falling in the low frequencies-red noise. An information analysis of the predictability of a series of inter-response times (IRTs) reveals that there is some gain in prediction by knowing past behavior; moreover, predictability increases the more past behaviors are taken into account. However, the further into the future these predictions are extended, the less reliable they become-entropy. These findings suggest that the dynamic controlling behavior at the level of the individual response is, to some extent, deterministic and probably chaotic.
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http://dx.doi.org/10.1016/s0376-6357(02)00043-8 | DOI Listing |
Bioprocess Biosyst Eng
January 2025
Cell Culture Development, Biogen, 5000 Davis Drive, Research Triangle Park, NC, 27709, USA.
Membrane fouling is a common and complex challenge with cell culture perfusion process in biopharmaceutical manufacturing that can have detrimental effects on the process performance. In this study, we evaluated a method to calculate the hollow fiber membrane resistance at different time points for water and supernatant. In addition, the number of subvisible particles of < 200 nm.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Albany Medical College, Albany, NY, USA.
Background: Stress is a common modifiable risk factor for AD, which increases dementia risk 2-fold. During the stress response, the hypothalamic-pituitary adrenal (HPA) axis is activated which stimulates the release of stress hormones called glucocorticoids into the blood stream. Studies on early-life stress have shown a glucocorticoid dependent vulnerability towards late-life inflammation.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre for Healthy Brain Ageing (CHeBA), University of New South Wales, UNSW Sydney, NSW, Australia.
Background: Social cognition is crucial to optimal social functioning outcomes in older adults, with implications for overall health and wellbeing. Moreover, poor social cognition is a diagnostic criterion for neurocognitive disorders (NCDs). Prior work has studied the social cognitive subdomains (theory of mind (ToM), affective empathy, emotion recognition, and social behaviour) and found mild cognitive impairment and dementia to be associated with poorer performance in specific tasks and informant-reported changes respectively.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Background: Mild Behavioral Impairment (MBI) is the onset of sustained neuropsychiatric symptoms that are considered as a possible precursor to neurodegenerative conditions, especially dementia. The concept of MBI recognizes that behavioral changes may be an early sign of brain changes due to neurodegeneration. Very recent research has shown behavioral changes in MBI might be linked to changes in brain structure, including cortical thickness.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Urology, National Taiwan University Hospital, No. 7, Zhongshan S. Rd., Zhongzheng Dist., Taipei, 100, Taiwan.
Patients with overactive bladder syndrome-wet (OAB-wet) experience urgency urinary incontinence, particularly urinary frequency and nocturia. Nocturnal enuresis (NE) is less addressed among OAB-wet patients. The study evaluated the prevalence of NE, lower urinary tract symptoms (LUTS), urodynamic factors, and social factors in OAB-wet patient.
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