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HemaScope: A Tool for Analyzing Single-cell and Spatial Transcriptomics Data of Hematopoietic Cells.
Genomics Proteomics Bioinformatics
January 2025
Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Research Unit of Hematologic Malignancies Genomics and Translational Research of Chinese Academy of Medical Sciences, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) techniques hold great value in evaluating the heterogeneity and spatial characteristics of hematopoietic cells within tissues. These two techniques are highly complementary, with scRNA-seq offering single-cell resolution and ST retaining spatial information. However, there is an urgent demand for well-organized and user-friendly toolkits capable of handling single-cell and spatial information.
View Article and Find Full Text PDFComputational analysis of linear chain of holey nanographene and their molecular characterizations.
J Mol Model
January 2025
PG & Research Department of Mathematics, Sanatana Dharma College, Kerala University, Alappuzha, Kerala, 688003, India.
Holey nanographene, an allotrope of carbon arranged in two dimensions, has gained remarkable attention as a nanomaterial with several potential uses in numerous industries, such as electronics, energy storage, healthcare, and environmental cleanup, because of its high carrier mobility, flexibility, transparency, high surface area, conductivity, and chemical stability. The fundamental holey nanographene is assembled in a linear form to create the holey nanographene chain (HNC) that is being discussed. To fully utilize it in various applications, it is essential to comprehend the basic ideas guiding its behavior at the nanoscale; for that, we find various topological indices for this holey nanographene chain using the cut method.
View Article and Find Full Text PDFSilver -Heterocyclic Carbene (NHC) Complexes as Antimicrobial and/or Anticancer Agents.
Pharmaceuticals (Basel)
December 2024
Department of Chemistry and Biology "A. Zambelli", University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.
The strict connections/interactions between microbial infections and cancer are nowadays widely accepted. Hence, the dual (or multiple) targeting of microbial infections and cancer is an essential issue to be addressed. In this context, metal complexes have gained considerable importance and effectiveness in medicinal chemistry.
View Article and Find Full Text PDFStudy of Ultrasound-Assisted Low-Pressure Closed Acid Digestion Method for Trace Element Determination in Rock Samples by Inductively Coupled Plasma Mass Spectrometry.
Molecules
January 2025
Institute of Mineral Resources, Chinese Academy of Geological Sciences, Beijing 100037, China.
In this paper, a method of ultrasound-assisted low-pressure closed acid digestion followed by inductively coupled plasma mass spectrometry (ICP-MS) analysis was proposed for trace element quantification in rock samples. By using 1.5 mL of a binary acid mixture of HNO-HF with a ratio of 2:1, rock powder samples of 50 mg were completely decomposed in 12 h at 140 °C after 4 h of ultrasonic treatment with or without pressure relief procedure.
View Article and Find Full Text PDFMechanical Strength and Mechanism Analysis of Silt Soil Cured by Straw Ash-Calcium Carbide Slag.
Materials (Basel)
January 2025
Heilongjiang Provincial Key Laboratory of Road Structure and Green Ecological Technology, Northeast Forestry University, Harbin 150090, China.
Large-scale engineering projects frequently involve pit excavation and wetland landfill operations, resulting in significant silt accumulation that occupies land and adversely affects the environment. Curing technology offers a solution for reusing this waste silt. In this study, straw ash and calcium carbide slag are proposed as effective curing agents for silt soil.
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