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Nanoporous Graphene Integrated onto Bimodal Waveguide Biosensors for Detection of C-Reactive Protein.
ACS Appl Nano Mater
January 2025
Atomic Manipulation and Spectroscopy Group (AMS), Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Bellaterra, 08193 Barcelona, Spain.
Despite the outstanding progress in photonic sensor devices, a major limitation for its application as label-free biosensors for biomedical analysis lies in the surface biofunctionalization step, that is, the reliable immobilization of the biorecognition element onto the sensor surface. Here, we report the integration of bottom-up synthesized nanoporous graphene onto bimodal waveguide interferometric biosensors as an atomically precise biofunctionalization scaffold. This combination leverages the high sensitivity of bimodal waveguide interferometers and the large functional surface area of nanoporous graphene to create highly sensitive, selective, and robust biosensors for the direct immunoassay detection of C-reactive protein (CRP), an inflammatory biomarker widely used in the clinical diagnosis of infections and sepsis.
View Article and Find Full Text PDFMechanical Considerations and Clinical Implications of Joint Arthroplasty Metallosis.
Cureus
December 2024
Orthopedic Surgery, Middlebrook Family Medicine, Middlebrook, USA.
The treatment for osteoarthritis (OA) often requires total joint arthroplasty (TJA) when less invasive approaches fail. The annual incidence of TJA is rising. Metal-on-metal (MoM) hip and knee implants were widely used for TJA in the past, but complications have led to their decline.
View Article and Find Full Text PDFAn eastern Congolian endemic, or widespread but secretive? New data on the recently described (Anura, Hyperoliidae) from the Democratic Republic of the Congo.
Zookeys
January 2025
Institute of Vertebrate Biology of the Czech Academy of Sciences, Brno, Czech Republic Institute of Vertebrate Biology of the Czech Academy of Sciences Brno Czech Republic.
The Great Lakes spiny reed frog () was recently described from transitional (submontane) forests at mid-elevations of the Albertine Rift mountains in the eastern Congolian region. Previously, because of its similarity, it had been understood to represent eastern populations of the unrelated , which is known mainly from Cameroon. Based on DNA barcoding, we document the westward extension of the known range of within lowland rainforests in the Northeastern and Central Congolian Lowland Forests.
View Article and Find Full Text PDFUncovering mercury accumulation and the potential for bacterial bioremediation in response to contamination in the Singalila National Park.
Sci Rep
January 2025
Molecular Biology and Tissue Culture Laboratory, Department of Tea Science, University of North Bengal, Siliguri, West Bengal, India.
Several recent investigations into montane regions have reported on excess mercury accumulation in high-altitude forest ecosystems. This study explored the Singalila National Park, located on the Singalila ridge of the Eastern Himalayas, revealing substantial mercury contamination. Particular focus was on Sandakphu (3636 m), the highest peak in West Bengal, India.
View Article and Find Full Text PDFFTW SERS probes with Ag NCs-GO composite structure excited by evanescent wave for in situ detection of permethrin.
Anal Chim Acta
March 2025
Zhejiang Key Laboratory of Advanced Optical Functional Materials and Devices, Ningbo University, Ningbo, 315211, China; Engineering Research Center for Advanced Infrared Photoelectric Materials and Devices of Zhejiang Province, Ningbo University, Ningbo, 315211, China. Electronic address:
Background: Permethrin is a pesticide used to kill insects, and once used in excess, it poses a great threat to the environment and human health, therefore, it is necessary to realize the rapid and accurate detection of permethrin. Fiber optic surface enhanced Raman scattering (SERS) probes have the advantages of small volume and can be used for remote monitoring, which have great potential for application in achieving in-situ detection of pesticide residues.
Results: Fiber taper waist (FTW) SERS probes modified by silver nanocubes-graphene oxide (Ag NCs-GO) composite structures were prepared for in situ detection of permethrin in lake water.
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