AI Article Synopsis
- The study reviewed trends in Candida species causing bloodstream infections across 99 medical centers in Spain and Argentina from 1996 to 1999, finding that non-albicans species were more prevalent than C. albicans in both countries.
- Key findings included that C. albicans was isolated in 30.2% (Spain) and 40.9% (Argentina) of cases, with C. parapsilosis being the second most common pathogen, while susceptibility to common antifungals varied significantly, especially in Argentinian isolates.
- The research highlighted the importance of ongoing surveillance for Candida infections and confirmed the reliability of the EUCAST protocol for antifungal susceptibility testing, showing strong interlaboratory
Article Abstract
The aim of this study was to identify retrospectively trends in species distribution and susceptibility patterns of Candida species causing bloodstream infections in 99 medical centres (55 in Spain and 44 in Argentina) from 1996 to 1999. A total of 744 Candida isolates were sent to the mycology reference laboratories during the study period (514 to the Spanish laboratory and 230 to the Argentinian laboratory). Candida non-albicans strains caused more episodes of fungaemia than Candida albicans isolates in both Spain and Argentina. C. albicans was isolated in 30.2% (155/514) and 40.9% (94/230) of episodes in Spain and in Argentina, respectively. In addition, Candida parapsilosis was the second most commonly isolated pathogen (36.4%). Candida tropicalis caused 13.7% of infections and Candida glabrata 7.4%. The amphotericin B MIC was
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http://dx.doi.org/10.1093/jac/dkf060 DOI Listing Publication Analysis
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