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Can a brief guided nature walk reduce distress and improve resilience, mindful attention, and sleep quality? Evidence from a pilot study with two-week follow-up.
Int J Environ Health Res
January 2025
Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Despite trends of deteriorating mental health globally, help-seeking remains suboptimal. Identifying less stigmatising, low-cost, and scalable approaches to mental health care is critical. We investigated the acceptability and psychological benefits of a 30-minute guided nature walk programme in an accessible country park in Hong Kong among 100 community members.
View Article and Find Full Text PDFThe Impact of Inflammatory Cytokines on Recurrent Pregnancy Loss: A Preliminary Investigation.
Reprod Sci
January 2025
Department of Anatomy, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Recurrent pregnancy loss (RPL), defined as two or more consecutive miscarriages before 20 weeks of gestation, affects 1-2% of couples worldwide. Pro-inflammatory cytokines, such as TNF-α, IL-1β and IL-6 play critical roles in early pregnancy, while anti-inflammatory cytokines like TGF-β and IL-10 promote immune tolerance to prevent harmful inflammatory responses that play important role in placental and fetal development. This aim of the study is to analyse the levels of inflammatory cytokines in blood serum from RPL patients and healthy women (control).
View Article and Find Full Text PDFValidating the RISE Communication Play Protocol as a Diagnostic Tool for Autism in Early Childhood: A Pilot Study.
J Autism Dev Disord
January 2025
Department of Psychology, University of Massachusetts Boston, Boston, MA, USA.
There are few validated remote tools that can be used to assess for autism and to capture subtle changes in children's social communication over time. Recently, user-centered design principles were applied to develop a parent-mediated remote assessment, the Reciprocal Imitation and Social Engagement Child Play Protocol (RISE CPP) to enable researchers to capture micro-level behaviors in children, while promoting useability for researchers and families, reducing caregiver burden, and maintaining reliability. This paper describes a pilot study to validate the RISE CPP as a tool to support clinician diagnosis of autism.
View Article and Find Full Text PDFAn Integrated Strategy for Deciphering the Action Mechanism of Emplastrum: Prescription Analysis- Component Identification- Virtual Screening and Affinity Testing in the Case of Yaoshen Gao.
J Ethnopharmacol
January 2025
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China. Electronic address:
Ethnopharmacological Relevance: Emplastrum has a long history of use in the clinical practice of traditional Chinese medicine (TCM), valued for its convenient external application and pronounced therapeutic effects. Traditionally, the emplastrum was composed of numerous herbal medicines. The elucidation of their mechanisms of action are of great importance.
View Article and Find Full Text PDFObservational studies on per- and polyfluoroalkyl substance toxicity in marine species: hints for the extrapolation of a screening value.
Environ Toxicol Chem
January 2025
Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Italy.
A statistical procedure has been developed to derive a screening value from an observational study related to the developmental toxicity observed in loggerhead turtle (Caretta caretta) eggs exposed to long chain per- and polyfluoroalkyl substances (PFAS). A dataset of 41 nests in which the hatching rate was inversely correlated with the increase in the PFAS concentration in unhatched eggs was processed via a categorical regression approach. After outliers identification and removal, categorical regression analysis tested the relationships of the outcomes with the following parameters: perfluoro-nonanoic (PFNA), decanoic (PFDA), undecanoic (PFUdA), and dodecanoic (PFDoA) acids; perfluoroctansulfonate (PFOS); polychlorobiphenyls (PCBs) 28, 52, 101, 138, 153, 180; lead (Pb), total mercury (Hgtot), and cadmium (Cd); and other factors, such as "nest site," "clutch size," "incubation duration," and "nest minimum depth," as confounders/modifiers of the hatching rate.
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