Monosomy 15 in chronic myelomonocytic leukemia. description of a case and review of the literature.

Cancer Genet Cytogenet

Laboratori de Citogenètica i Biologia Molecular, Departament de Patologia, Hospital del Mar, Pg Marítim, 25-29, 08003, Barcelona, Spain.

Published: April 2002

We report a 89-year-old female diagnosed with chronic myelomonocytic leukemia (CMMoL) presenting with a monosomy 15. To our knowledge, this is the second reported case of CMMoL with monosomy 15. On the other hand, monosomy 15 in complex karyotypes is a frequent chromosome aberration in myelodysplastic syndromes, particularly in refractory anemia with excess of blasts.

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http://dx.doi.org/10.1016/s0165-4608(01)00629-xDOI Listing

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