We describe the nearly quantitative preparation of phosphorus ylides and the Wittig reaction occurring in the solid sate during high-energy mechanochemical processing. Initial insights into the details of the discovered chemical transformations indicate that high-energy mechanical processing supports the interaction of reacting centers by breaking crystallinity of the reactants and by providing mass transfer without a solvent.
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Article Synopsis
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- Recent research introduces a new ligand, N-heterocyclic olefin phosphines with sulfonyl substituents (sNHOP), which twists a double bond to create a zwitterionic structure.
- This new ligand shows improved donor strength and has proven effective in gold-catalyzed reactions, surpassing traditional NHOP ligands in performance, indicating strong potential for future catalytic applications.
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