In order to understand the dynamics of the India Asia collision zone, it is important to know the strain distribution in Central Asia, whose determination relies on the slip rates for active faults. Many previous slip-rate estimates of faults in Central Asia were based on the assumption that offset landforms are younger than the Last Glacial Maximum (approximately 20 kyr ago). In contrast, here we present surface exposure ages of 40 to 170 kyr, obtained using cosmogenic nuclide dating, for a series of terraces near a thrust at the northern margin of the Tibetan Plateau. Combined with the tectonic offset, the ages imply a long-term slip rate of only about 0.35 mm x yr(-1) for the active thrust, an order of magnitude lower than rates obtained from the assumption that the terraces formed after the Last Glacial Maximum. Our data demonstrate that the preservation potential of geomorphic features in Central Asia is higher than commonly assumed.
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http://dx.doi.org/10.1038/417428a | DOI Listing |
Front Pharmacol
January 2025
Department of Pharmacy, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China.
Background: Stroke is the leading cause of disability globally, with antiplatelet therapy being crucial for secondary prevention but also increasing bleeding risks. This requires careful dosage adjustments to balance thrombosis and bleeding risks.
Objective: This study compared the efficacy and safety of low-dose versus standard-dose antiplatelet therapy in stroke patients.
Front Cardiovasc Med
January 2025
State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Background: Few studies have examined the relationship between nutritional status, as assessed by the Prognostic Nutrition Index (PNI), and incident cardiovascular mortality and all-cause mortality, particularly in hypertensive patients. This study aimed to examine the association between PNI and cardiovascular mortality and all-cause mortality in Americans with hypertension.
Methods: Data from this retrospective cohort study were obtained from the National Health and Nutrition Examination (NHANES) 1999-2016.
Front Microbiol
January 2025
College of Grassland Science, Xinjiang Agricultural University, Urumqi, China.
Iron (Fe) minerals possess a huge specific surface area and high adsorption affinity, usually considered as "rust tanks" of organic carbon (OC), playing an important role in global carbon storage. Microorganisms can change the chemical form of Fe by producing Fe-chelating agents such as side chains and form a stable complex with Fe(III), which makes it easier for microorganisms to use. However, in seasonal frozen soil thawing, the succession of soil Fe-cycling microbial communities and their coupling relationship with Fe oxides and Fe-bound organic carbon (Fe-OC) remains unclear.
View Article and Find Full Text PDFInt Breastfeed J
January 2025
Behavioural and Cultural Insights Unit, WHO Regional Office for Europe, Copenhagen, Denmark.
Background: The WHO/UNICEF global nutrition target for exclusive breastfeeding for six months is at least 70% of infants by 2030. However, global prevalence rates are 48% with variations between countries and within regions. Kyrgyzstan has consistently high early breastfeeding initiation rates, yet exclusive breastfeeding for six months is 46%.
View Article and Find Full Text PDFJ Perinatol
January 2025
Faculty of Health Science and Medicine, University of Lucerne, Lucerne, Switzerland.
The perinatal period is associated with high antibiotic exposure, which raises concerns about antimicrobial resistance (AMR) and future health impacts. The aim of this comprehensive systematic review, including publications from 2000 to 2022, is to describe the current evidence and state of antimicrobial stewardship (AMS) in the perinatal period and to identify gaps in knowledge for future research. The review included 36 studies from the Americas, Europe, Asia and Australia, involving a total of 64,798 pregnant women and 84,137 newborns.
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