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This article analyzes the published testimonies of French shipwreck survivors to trace the emergence of a settler colonial ideal in nineteenth-century France. Emerging from the encounters of French survivors with the men of the Anglo-World, this ideal encouraged compassionate, paternalist authority as a solution to the ongoing conflict of paternal despotism and disorderly fraternal freedom in France. The community of sentiment imagined in shipwreck testimonies was gendered and racialized, cultivating white compassion across colonial empires.
View Article and Find Full Text PDFUnmasking the potential: a historical perspective on the evolution of exfoliative cytology in oral cavity neoplasms.
Minerva Dent Oral Sci
January 2025
Department of Biomedical and Dental Sciences, Morphological and Functional Images, G. Martino University Hospital, University of Messina, Messina, Italy.
Exfoliative cytology has proven to be a valuable diagnostic tool in the early detection of malignant neoplasms. However, its application in the oral cavity has been met with skepticism and limited investigation due to the perception that clinical examination alone is sufficient for early diagnosis. Nonetheless, recent research efforts have focused on the utility of exfoliative cytology in oral cavity neoplasms, motivated by the high mortality rate associated with oral cancer.
View Article and Find Full Text PDFDisparities in Alcohol-Associated Liver Disease Hospital Encounters Amongst a Texas-Based Cohort of Patients.
Aliment Pharmacol Ther
January 2025
Division of Digestive and Liver Diseases, UT Southwestern Medical Center, Dallas, Texas, USA.
Introduction: Alcohol-associated liver disease (ALD) disproportionately impacts men, racial and ethnic minorities, and individuals of low socioeconomic status; however, it's unclear how recent increases in ALD burden have impacted these disparities. We aimed to describe trends in racial, ethnic and socioeconomic disparities in alcohol-associated hospital encounters.
Methods: We conducted a retrospective cohort study of adult hospital encounters with alcohol-associated diagnoses from three health systems between January 2016 and December 2021.
The evolution of the Amber additive protein force field: History, current status, and future.
J Chem Phys
January 2025
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Frontiers Science Center of Molecule Intelligent Syntheses, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
Molecular dynamics simulations are pivotal in elucidating the intricate properties of biological molecules. Nonetheless, the reliability of their outcomes hinges on the precision of the molecular force field utilized. In this perspective, we present a comprehensive review of the developmental trajectory of the Amber additive protein force field, delving into researchers' persistent quest for higher precision force fields and the prevailing challenges.
View Article and Find Full Text PDFAncient DNA reveals reproductive barrier despite shared Avar-period culture.
Nature
January 2025
Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
After a long-distance migration, Avars with Eastern Asian ancestry arrived in Eastern Central Europe in 567 to 568 CE and encountered groups with very different European ancestry. We used ancient genome-wide data of 722 individuals and fine-grained interdisciplinary analysis of large seventh- to eighth-century CE neighbouring cemeteries south of Vienna (Austria) to address the centuries-long impact of this encounter. We found that even 200 years after immigration, the ancestry at one site (Leobersdorf) remained dominantly East Asian-like, whereas the other site (Mödling) shows local, European-like ancestry.
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