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Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas. | LitMetric

AI Article Synopsis

  • ZAP36 is a 36 kDa protein from zymogen granules found in the pancreas of both dogs and rats.
  • This protein is identified as a new member of the annexin IV family and is primarily located at the apical part of the exocrine pancreas while being widely expressed in epithelial tissues.
  • ZAP36 is believed to play a role in the process of exocytosis within the apical regions of polarized cells.

Article Abstract

ZAP36, a zymogen granule membrane associated protein with 36 kDa, was cloned from both canine and rat pancreas. ZAP36 is found to be a novel member of annexin IV, and showed an apical localization in exocrine pancreas and an ubiquitous expression in epithelial tissues. ZAP36 may be involved in exocytosis in apical regions of polarized cells.

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Source
http://dx.doi.org/10.1016/s0167-4781(02)00299-3DOI Listing

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