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Rapid determination of etomidate and its structural analogues in e-liquid by probe electrospray ionization quadrupole time-of-flight mass spectrometry.
J Pharm Biomed Anal
January 2025
Key Laboratory of Forensic Medicine, Ministry of Justice, Shanghai Forensic Service Platform, Shanghai Key Laboratory of Forensic Science, Academy of Forensic Science, Guangfu West Road 1347, Shanghai 200063, China. Electronic address:
Etomidate and its structural analogues, which have anesthetic effects, are classified as controlled psychotropic drugs. Electronic cigarettes (e-cigarettes) have become more and more popular. With the increase of adding etomidate and its analogues to electronic liquids (e-liquids), there is a trend of abuse, which is a tough problem urgently need to be solved.
View Article and Find Full Text PDFEnhanced flame retardancy and accelerated degradation of polylactic acid using a chitosan-based additive with phosphorus and zinc.
Int J Biol Macromol
December 2024
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China. Electronic address:
Polylactic acid (PLA) is a bio-recyclable plastic, but its high flammability limits broader applications. Here, a novel flame retardant (Zn-CHP) is synthesized from chitosan (CH), diethylenetriaminepenta (methylenephosphonic) acid (DTPMP), and ZnCl₂ using a simple, solvent-free process. The Zn-CHP additive is melt-blended with PLA, achieving excellent flame retardancy at just 2 wt% loading.
View Article and Find Full Text PDFPerformance assessment of solar tower collector based integrated system for the cogeneration of power and cooling.
Heliyon
November 2024
Department of Electrical Engineering, College of Engineering, Majmaah University, Al-Majmaah, 11952, Saudi Arabia.
Integrating solar energy systems is an essential measure in advancing worldwide sustainability objectives and offers a sustainable, environmentally friendly approach to reducing greenhouse gas emissions and pollutants. To this direction, the proposed system integrating solar tower collector, supercritical CO, organic Rankine cycle, and single effect absorption refrigeration cycles shows potential as an efficient and sustainable solution for meeting energy and cooling demands. A detailed thermodynamic evaluation has been performed to gain valuable understanding of the energy and exergy performance, enabling the assessment of thermal and exergy efficiencies, exergy destructions, and heat losses.
View Article and Find Full Text PDFA Feasibility Trial on Intranasal Evaporative Cooling for Acute Migraine in an At-Home Setting.
Cureus
November 2024
Department of Clinical Sciences, Lund University, Malmö, SWE.
Article Synopsis
- - The study aimed to assess the feasibility of self-administering intranasal evaporative cooling for acute migraine relief at home, following previous success in a clinic setting.
- - Conducted in southern Sweden, the trial involved 15 participants with episodic migraine, but only 6 completed the study due to discomfort and ineffective results.
- - Findings indicated that the treatment was largely considered unpleasant and not significantly more effective than existing care methods, leading to the conclusion that it is not a viable option for home use.
Establishing A Mouse Model for Respiratory Tract Extreme Low-temperature Air Inhalation.
J Vis Exp
November 2024
Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University;
Currently, constructing a mouse model for cold environmental stimulation employs cold-heat plates and wearable cooling devices. These methods can partially fulfill the requirements for studying the responses and regulatory effects of mouse skin or neural circuits to cold stimulation. Numerous clinical studies have substantiated the correlation between exposure to low-temperature environments and the development of various diseases.
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