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Similar Publications

The evolving role of head up tilt test: New protocol and indications for optimizing the care of syncope patients.

Eur J Intern Med

January 2025

IRCCS Istituto Auxologico Italiano, Faint & Fall programme, Cardiology Unit and Department of Cardiovascular, Neural and Metabolic Sciences, S. Luca Hospital, Milan, Italy.

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Vasovagal Syncope: A Review of Current and Emerging Therapies for a Common Cardiology Condition.

J Tehran Heart Cent

January 2024

Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Vasovagal syncope (VVS), characterized by transient loss of consciousness, is among the most prevalent reasons for emergency visits worldwide. Although benign in nature, VVS can be accompanied by traumatic injury, leading to morbidity and decreased quality of life, especially in those with VVS recurrence. The management includes non-pharmacologic and pharmacologic therapies (if resistant), patient education and reassurance, salt and fluid intake increase, and physical counter-pressure maneuvers.

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The head-up tilt (HUT) test assesses both cardiovascular autonomic regulation and cerebral autoregulation. This exploratory study examined age-related changes in cardiovascular and cerebrovascular responses during the HUT test in three healthy cohorts (young, middle-aged, and elderly). We recruited 2342 neurologist-diagnosed 'normal' individuals from 18 June 2014 to 25 February 2022.

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There are several mechanisms responsible for the dynamical link between heart period (HP) and respiration (R), usually referred to as cardiorespiratory coupling (CRC). Historically, diverse signal processing techniques have been employed to study CRC from the spontaneous fluctuations of HP and respiration (R). The proposed tools differ in terms of rationale and implementation, capturing diverse aspects of CRC.

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Amyloid light chain (AL) amyloidosis is a disease in which ALs, which are proteins with fibrous structures, are deposited in systemic organs, causing functional impairment. Diagnosis is often difficult because of non-specific and varied symptoms. We report a case of systemic AL amyloidosis that was diagnosed as a result of repeated syncope.

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