Reconstructing the density fluctuations in the early Universe that evolved into the distribution of galaxies we see today is a challenge to modern cosmology. An accurate reconstruction would allow us to test cosmological models by simulating the evolution starting from the reconstructed primordial state and comparing it to observations. Several reconstruction techniques have been proposed, but they all suffer from lack of uniqueness because the velocities needed to produce a unique reconstruction usually are not known. Here we show that reconstruction can be reduced to a well-determined problem of optimization, and present a specific algorithm that provides excellent agreement when tested against data from N-body simulations. By applying our algorithm to the redshift surveys now under way, we will be able to recover reliably the properties of the primeval fluctuation field of the local Universe, and to determine accurately the peculiar velocities (deviations from the Hubble expansion) and the true positions of many more galaxies than is feasible by any other method.
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http://dx.doi.org/10.1038/417260a | DOI Listing |
J Hand Surg Eur Vol
January 2025
Clinical Scientific Computing, Guy's and St Thomas' NHS Foundation Trust, London, UK.
This paper discusses the current literature surrounding the potential use of artificial intelligence and machine learning models in the diagnosis of acute obvious and occult scaphoid fractures. Current studies have notable methodological flaws and are at high risk of bias, precluding meaningful comparisons with clinician performance (the current reference standard). Specific areas should be addressed in future studies to help advance the meaningful and clinical use of artificial intelligence for radiograph interpretation.
View Article and Find Full Text PDFEur Heart J Digit Health
January 2025
Department of Cardiovascular Surgery of Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Aims: Accurate heart function estimation is vital for detecting and monitoring cardiovascular diseases. While two-dimensional echocardiography (2DE) is widely accessible and used, it requires specialized training, is prone to inter-observer variability, and lacks comprehensive three-dimensional (3D) information. We introduce CardiacField, a computational echocardiography system using a 2DE probe for precise, automated left ventricular (LV) and right ventricular (RV) ejection fraction (EF) estimations, which is especially easy to use for non-cardiovascular healthcare practitioners.
View Article and Find Full Text PDFEur Heart J Digit Health
January 2025
Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest 1122, Hungary.
JPRAS Open
March 2025
Department of Plastic Surgery, Cleveland Clinic, Ohio, USA.
Breast revision surgery is often necessary in patients following postmastectomy breast reconstruction with free autologous flaps for aesthetic improvement. Indications for nipple-sparing mastectomy continue to be expanded oncologically. However, revision techniques for aesthetic concerns following breast reconstruction are underreported in the literature.
View Article and Find Full Text PDFJPRAS Open
March 2025
Sir Charles Gairdner Hospital, Nedlands, Perth, Western Australia, 6009.
Background: Trunk reconstruction following sarcoma excision involves significant defects. Pedicled and free latissimus dorsi myocutaneous flap (LDMF) reconstruction is commonly employed for thoracic defects; however, skin paddle design is limited to 10-12 cm to achieve primary donor closure. Paucity of data exists regarding the utility of V-Y advancement of LDMF, previously described for moderately sized thoracic defects.
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