After staying in real and simulated weightlessness, the most obvious changes were recorded in the "slow" tonic muscles like m. soleus, the protein loss in the fibres being greater than the loss of other components, water included.
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Stomatologiia (Mosk)
January 2025
A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia.
The Purpose: Of the study was to assess oral microbiocenosis changes in participants of microgravity modeling in a control group and using prophylaxis in the form of a probiotic supplement with 1.0·10 CFU of strain in one lozenge and a dairy product containing not less than 1·10 CFU of s strain in one gram.
Materials And Methods: The study included 15 participants aged 25-40 years from the "Dry Immersion-2018" experiment.
FASEB J
January 2025
National Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Microgravity-induced cardiac remodeling and dysfunction present significant challenges to long-term spaceflight, highlighting the urgent need to elucidate the underlying molecular mechanisms and develop precise countermeasures. Previous studies have outlined the important role of miRNAs in cardiovascular disease progression, with miR-199a-3p playing a crucial role in myocardial injury repair and the maintenance of cardiac function. However, the specific role and expression pattern of miR-199a-3p in microgravity-induced cardiac remodeling remain unclear.
View Article and Find Full Text PDFPerception
January 2025
Hebei Normal University, China.
Exposure to microgravity induces abnormal experiences that may affect the perception of time. Head-down tilts (HDTs) are commonly used to investigate the effects of weightlessness. A -30° HDT is considered an appropriate model to simulate the acute phase of microgravity exposure.
View Article and Find Full Text PDFPlants will form the basis of artificial ecosystems in space exploration and the creation of bases on other planets. Astrophysical factors, such as ionizing radiation (IR), magnetic fields (MF) and gravity, can significantly affect the growth and development of plants beyond Earth. However, to date, the ways in which these factors influence plants remain largely unexplored.
View Article and Find Full Text PDFWorld J Gastroenterol
January 2025
Department of Gastroenterology, The Air Force Medical Center, Beijing 100142, China.
Background: Simulated microgravity environment can lead to gastrointestinal motility disturbance. The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor (SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal cells. Moreover, intestinal flora can also affect the regulation of SCF/c-kit signaling pathway, thus affecting the expression of Cajal stromal cells.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!