AI Article Synopsis
- The study aims to compare the effectiveness of one vs. two monthly insertions of quinacrine for female sterilization.
- The research involved 100 sexually active women at family planning clinics and tracked them for a year, assessing complications and pregnancy rates.
- Results showed higher pregnancy failure rates with one insertion (7.4%) compared to two (1.1%), with both methods being safe and manageable in terms of side effects.
Article Abstract
Objective: To determine the relative effectiveness of single vs. two transcervical monthly insertions of 252 mg of quinacrine for female sterilization.
Design: Controlled clinical study.
Setting: Family planning clinics of 6 academic centers.
Patient(s): Sexually active reproductive-age women requesting sterilization.
Intervention(s): At each of six centers 70 and 30 women were randomly assigned to receive either one or two, respectively, monthly transcervical insertions to the fundus of 252 mg of quinacrine and 75 mg of diclofenac as pellets and they were followed for 1 year.
Main Outcome Measure(s): Complications, side effects, and pregnancy failures.
Result(s): There were no serious complications and side effects were transient and easily treated. There were 31 (7.4%) pregnancy failures in the single insertions group and 2 (1.1%) in the two insertions group, but with marked center variation.
Conclusion(s): Quinacrine sterilization using two monthly insertions of 252 mg of quinacrine appears safe and reasonably effective.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0015-0282(02)02957-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!